ナガオ　ミチノブ   Nagao Michinobu   長尾　充展    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Evaluation of ventricular dysfunction using semi-automatic longitudinal strain analysis of four-chamber cine MR imaging.
掲載誌名	正式名：The international journal of cardiovascular imaging 略　 称：Int J Cardiovasc Imaging ISSNコード：(1875-8312)1569-5794(Linking)
掲載区分	国外
巻・号・頁	32(2),pp.283-289
著者・共著者	Kawakubo Masateru, Nagao Michinobu, Kumazawa Seiji, Yamasaki Yuzo, Chishaki Akiko S, Nakamura Yasuhiko, Honda Hiroshi, Morishita Junji
発行年月	2016/02
概要	The aim of this study was to evaluate ventricular dysfunction using the longitudinal strain analysis in 4-chamber (4CH) cine MR imaging, and to investigate the agreement between the semi-automatic and manual measurements in the analysis. Fifty-two consecutive patients with ischemic, or non-ischemic cardiomyopathy and repaired tetralogy of Fallot who underwent cardiac MR examination incorporating cine MR imaging were retrospectively enrolled. The LV and RV longitudinal strain values were obtained by semi-automatically and manually. Receiver operating characteristic (ROC) analysis was performed to determine the optimal cutoff of the minimum longitudinal strain value for the detection of patients with cardiac dysfunction. The correlations between manual and semi-automatic measurements for LV and RV walls were analyzed by Pearson coefficient analysis. ROC analysis demonstrated the optimal cut-off of the minimum longitudinal strain values (εL_min) for diagnoses the LV and RV dysfunction at a high accuracy (LV εL_min = -7.8 %: area under the curve, 0.89; sensitivity, 83 %; specificity, 91 %, RV εL_min = -15.7 %: area under the curve, 0.82; sensitivity, 92 %; specificity, 68 %). Excellent correlations between manual and semi-automatic measurements for LV and RV free wall were observed (LV, r = 0.97, p < 0.01; RV, r = 0.79, p < 0.01). Our semi-automatic longitudinal strain analysis in 4CH cine MR imaging can evaluate LV and RV dysfunction with simply and easy measurements. The strain analysis could have extensive application in cardiac imaging for various clinical cases.
DOI	10.1007/s10554-015-0771-2
PMID	26384485