マナベ シユン   Manabe Shiyun
  眞部 俊
   所属   医学部 医学科(東京女子医科大学病院)
   職種   講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Bucillamine-induced membranous nephropathy with crescent formation in a patient with rheumatoid arthritis: case report and literature review.
掲載誌名 正式名:Case reports in nephrology and dialysis
略  称:Case Rep Nephrol Dial
ISSNコード:2296-9705(Electronic)
巻・号・頁 5(1),pp.30-8
著者・共著者 Manabe Shun†, Banno Mayuko, Nakano Marie, Fujii Teruhiro, Fujiwara Michio, Kita Yasuhiko, Nitta Kosaku, Hatano Michiyasu
担当区分 筆頭著者
発行年月 2015/07
概要 Bucillamine is a disease-modifying antirheumatic drug that is structurally similar to D-penicillamine. The major renal side effect of bucillamine and D-penicillamine is proteinuria caused by membranous nephropathy (MN). In addition to MN, combined crescent formation has been occasionally reported in D-penicillamine-induced MN, while crescent formation has been rarely reported in bucillamine-treated cases. Here, we describe a 76-year-old female who presented with nephrotic syndrome and rapidly progressive glomerulonephritis. She was receiving bucillamine as initial treatment for recently diagnosed rheumatoid arthritis, and renal biopsy showed MN with crescent formation. To the best of our knowledge, this is the first report of bucillamine-induced MN with crescent formation in the English literature.
DOI 10.1159/000368826
文献番号 25849672