イセキ　ヒロシ   Iseki Hiroshi   伊関　洋    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   特任顧問
論文種別	その他
言語種別	日本語
査読の有無	査読なし
表題	[Clinical evaluation of intraoperative radiotherapy using photon radiosurgery system for brain tumors]
掲載誌名	正式名：Gan To Kagaku Ryoho ISSNコード：03850684
巻・号・頁	25(9),1348-1351頁
著者・共著者	久保長生†, 村垣善浩, 伊関洋, 高倉公朋
発行年月	1998/07
概要	The photon radiosurgery system is a miniature X-ray generator that can be placed stereotactically and intraoperatively into intracranial tumors to deliver a single fraction of high-dose interstitial irradiation. This battery-powered device produces low energy X-ray photons in a spherical and symmetrical pattern at the probe tip. Dose rates of up to 200 cGy/Mim are possible, allowing for the administration of 15 Gy to a lesion 3 cm in diameter in less than 1 hr. Background exposure is minimal, and no special shielding of the patient or health care personnel is required. Thirty-nine patients with brain tumor were treated in this method. There were no adverse effects. During the follow-up period of 1-30 months, 3 cases with 5 metastatic brain tumors died about 8 months after this treatment. Five recurrent cases of 21 malignant gliomas died about 4 months after treatment. Interstitial radiotherapy using photon the radiosurgery system promises to be a useful treatment for brain tumors.
文献番号	9703825