イセキ　ヒロシ   Iseki Hiroshi   伊関　洋    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   特任顧問
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Intraoperative tumor segmentation and volume measurement in MRI-guided glioma surgery for tumor resection rate control
掲載誌名	正式名：Academic Radiology ISSNコード：10766332
巻・号・頁	12(1),pp.116-122
著者・共著者	HATA Nobuhiko, MURAGAKI Yoshihiro, INIMATA Takashi , MARUYAMA Takashi, ISEKI Hiroshi, HORI Tomokatsu, DOHI Takeyoshi
発行年月	2005/11
概要	Gross-total surgery under intraoperative magnetic resonance imaging (MRI) is a promising method of glioma removal. The purpose of this article is intraoperative measurement of resected tumor volume in MRI-guided glioma surgery using semiautomatic image segmentation to unbiased resection rate control.|A newly developed software program based on a fuzzy connectedness (FC) segmentation algorithm was used to achieve fast and semiautomatic tumor segmentation and tumor volume measurement. The program was validated by retrospective study of eight glioma cases and then applied to seven glioma cases. All clinical cases underwent actual MRI-guided surgery using 0.3-T open magnets.|The volume of the tumor before resection ranged from 10.1 to 206.7 mL. A comparison of the results of manual segmentation with those of the semiautomatic FC-based segmentation gave an average dice similarity coefficient of 0.80 and an average match of 76%. Volume measurement combined with a developed software program enabled quantitative monitoring of tumor removal, which was critical in the near-total resection of glioma in MRI-guided surgery.|The FC-based tumor segmentation method can be used for intraoperative tumor segmentation and volume measurement in MRI-guided glioma surgery using 0.3-T open magnets. This method is useful for objective resection rate monitoring, which may ultimately minimize the amount of residual tumor in glioma surgery.
DOI	10.1016/j.acra.2004.11.009
文献番号	15691732