イセキ　ヒロシ   Iseki Hiroshi   伊関　洋    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   特任顧問
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Low-dose gamma knife radiosurgery for cavernous sinus hemangioma: report of 3 cases and literature review
掲載誌名	正式名：Minimally invasive neurosurgery : MIN 略　 称：Minim Invasive Neurosurg ISSNコード：09467211
掲載区分	国外
出版社	Georg Thieme Verlag KG Stuttgart · New York
巻・号・頁	51(3),pp.140-146
著者・共著者	Ivanov P†, CHERNOV Mikhail, HAYASHI Motohiro, NAKAYA Kotaro, IZAWA Masahiro, TAMURA Noriko, KUBO Osami, UJIIE Hiroshi, MURAGAKI Yoshihiro, NAKAMURA Ryoichi, ISEKI Hiroshi, HORI Tomokatsu, TAKAKURA Kintomo
発行年月	2008/07
概要	Optimal management of cavernous sinus hemangiomas remains unclear. Total microsurgical removal of these neoplasms may be extremely difficult due to their rich vascularization. Three cases of cavernous sinus hemangioma treated with low-dose Gamma Knife radiosurgery are presented. Marginal dose varied from 10 to 13 Gy. Treatment planning and radiation dosimetry were done with a goal of conformal and selective coverage of the lesion with 50% prescription isodose line using multiisocenter technique. In all cases significant shrinkage of the neoplasm was marked at 3 months after treatment. Mean volume reduction at 12 months after radiosurgery was 60% (range: 45-75%). In all patients the shrinkage of the neoplasm was accompanied by notable improvement of the preexistent oculomotor nerve palsy. No radiosurgery-related complications were met during follow-up. In conclusion, low-dose Gamma Knife radiosurgery seems to be very effective for management of cavernous sinus hemangiomas, and can be considered as a treatment modality of choice for these lesions.
DOI	10.1055/s-2008-1065346
文献番号	18521784