イセキ　ヒロシ   Iseki Hiroshi   伊関　洋    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   特任顧問
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Identification of the pyramidal tract by neuronavigation based on intraoperative diffusion-weighted imaging combined with subcortical stimulation
掲載誌名	正式名：Sterotactic and Functional Neurosurgery 略　 称：Stereotact Funct Neurosurg ISSNコード：1011-6125
掲載区分	国外
巻・号・頁	87(1),pp.18-24
著者・共著者	OZAWA Norihiko†, MURAGAKI Yoshihiro, NAKAMURA Ryoichi, ISEKI Hiroshi
発行年月	2009/02
概要	To identify the pyramidal tract by neuronavigation based on intraoperative diffusion-weighted imaging (iDWI) combined with subcortical stimulation.|Seven patients with brain tumors near the deep white matter underwent resection surgery using neuronavigation based on iDWI to visualize white matter bundles. Subcortical electrical stimulation was performed and electromyography was measured at the extremities when surgical manipulation came near the position corresponding to the depicted bundle. We validated the bundle depicted on iDWI by considering the responses to subcortical stimulation and the distance between the stimulation site and the depicted bundle.|Positive motor-evoked potentials were detected in 5 of 7 patients (8 stimulations) and the distance from the stimulation site to the depicted bundle was 0-4.7 mm (mean +/- SD, 1.4 +/- 2.1 mm). Negative (no) responses were obtained in all patients when the distance was more than 5 mm. The neuronavigation system had an average error of 0.79 +/- 0.25 mm and a maximum error of 2.0 mm (n = 16).|Neuronavigation based on iDWI combined with subcortical stimulation allowed surgeons to identify the pyramidal tract and avoid inadvertent injury. Our findings demonstrate that the white matter bundles depicted by iDWI can contain the pyramidal tract.
DOI	10.1159/000177624
PMID	19039259
PermalinkURL	https://www.karger.com/Article/Abstract/177624