イセキ　ヒロシ   Iseki Hiroshi   伊関　洋    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   特任顧問
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	"Donut's shape"radiosurgical treatment planning for large cystic metastatic brain tumors
掲載誌名	正式名：Minim Invasive Neurosurg ISSNコード：14392291
出版社	Georg Thieme Verlag KG Stuttgart
巻・号・頁	54(5-6),pp.286-289
著者・共著者	HAYASHI Motohiro†, CHERNOV Mikhail, TAMURA Manabu, IZAWA Masahiro, MURAGAKI Yoshihiro, ISEKI Hiroshi, OKADA Yoshikazu
発行年月	2011/10
概要	Radiosurgical management of large cystic metastatic brain tumors represents a significant challenge. Nevertheless, modified dose planning has shown beneficial results in such cases.|"Donut's shape"radiosurgical treatment planning is based on the chain-like application of multiple, small-sized isocenters for selective coverage of the contrast-enhancing tumor capsule and minimal irradiation of the central cystic area. Such an approach was used for the management of large cystic intracranial metastases, which were not accompanied by a significant mass effect and did not require immediate volume reduction. Treatment was done using Leksell Gamma Knife model C with automatic positioning system. The majority of treated lesions showed significant shrinkage after radiosurgery and no major complications were met.|Large cystic metastatic brain tumors may be successfully treated with gamma knife radiosurgery alone using the proposed"donut's shape"dose planning with coverage of the contrast-enhancing tumor capsule by multiple small-sized isocenters.
DOI	10.1055/s-0031-1297987
文献番号	22278800