イチハラ　アツヒロ   ICHIHARA Atsuhiro   市原　淳弘    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Association between soluble (Pro)renin receptor concentration in cord blood and small for gestational age birth: a cross-sectional study.
掲載誌名	正式名：PloS one 略　 称：PLoS One ISSNコード：1932-6203(Electronic)1932-6203(Linking)
巻・号・頁	8(3),pp.e60036
著者・共著者	WATANABE Noriyoshi†, MORIMOTO Satoshi, FUJIWARA Takeo, SUZUKI Tomo, TANIGUCHI Kosuke, ANDO Takashi, KIMURA Tadashi, SAGO Haruhiko, ICHIHARA Atsuhiro*
担当区分	責任著者
発行年月	2013/03
概要	OBJECTIVE:The (pro)renin receptor [(P)RROBJECTIVE:]OBJECTIVE:has been recognized as a multifunctional receptor. The purpose of this study was to assess the association between plasma soluble (P)RR [s(P)RROBJECTIVE:]OBJECTIVE:concentration in human cord blood (i.e., neonatal blood at birth) and small for gestational age (SGA) birth.METHODS:Participants wereMETHODS:women with a singleton pregnancy who delivered at the National Center for Child Health and Development between January 2010 and December 2011. Inclusion criteria were availability of maternal pre-pregnancy and paternal body mass index, and the absence of structural anomalies in neonates. s(P)RR concentration in cord blood was measured in 621 neonates. The 621 pairs of mothers and neonates were categorized into four groups based on quartiles of s(P)RR concentrations in cord blood. SGA was defined as a birth weight below the 10(th) percentile for gestational age. Logistic regression analysis was performed to assess the association between cord plasma s(P)RR concentration (quartiles) and incidence of SGA births.
DOI	10.1371/journal.pone.0060036
文献番号	23555874