ホシノ　タカオ   Hoshino Takao   星野　岳郎    所属   医学部 医学科（東京女子医科大学病院）    職種   講師
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Simultaneous development of acute disseminated encephalomyelitis and Guillain-Barre syndrome associated with H1N1 09 influenza vaccination
掲載誌名	正式名：Internal Medicine 略　 称：Intern Med ISSNコード：13497235
巻・号・頁	51(12),pp.1595-1598
著者・共著者	Hoshino Takaho†*, Uchiyama Yumiko, Ito Eiichi, Osawa Shunsuke, Ohashi Takashi
担当区分	筆頭著者,責任著者
発行年月	2012/06
概要	A 36-year-old man was admitted to our hospital because of urinary retention and muscle weakness affecting all 4 limbs after receiving a H1N1 09 influenza vaccination. Magnetic resonance imaging demonstrated multiple lesions in his brain and spinal cord. Furthermore, nerve conduction study showed acute sensorimotor neuropathy, and anti-GM2 antibodies were detected in his serum. Based on the temporal association and exclusion of alternative etiologies, we made a diagnosis of acute disseminated encephalomyelitis (ADEM) and Guillain-Barré syndrome (GBS). To our knowledge, this is the first case of co-morbid ADEM and GBS after influenza vaccination with positive anti-ganglioside antibodies.
DOI	10.2169/internalmedicine.51.7132