Faculty Information - NAKAI Yousuke

（Last updated : 2026-08-29 10:49:42）

NAKAI Yousuke
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Internal Medicine, Division of Gastroenterology

Position Professor and Division head

■ Published papers

1.	Original article	Usefulness of an S-1 dosage formula for predicting adverse events in adjuvant chemotherapy for curatively resected pancreatic cancer: an exploratory analysis of the randomized clinical trial (JASPAC-01) 2026/06
2.	Original article	Clinical Outcomes of Fontan-Associated Hepatocellular Carcinoma: a Single-Center Retrospective Study 2026/03
3.	Original article	Impact of a social media-based educational initiative on endoscopic practice in Vietnam: a survey study 2026/03
4.	Original article	Prognostic model for pancreatic cancer based on machine learning of routine slides and transcriptomic tumor analysis 2026/03
5.	Other	Reply to Vanella et al 2026/03
6.	Original article	Tacrolimus therapy for ulcerative colitis: a retrospective study of factors associated with inducing and maintaining remission 2026/03
7.	Original article	Endoscopic Ultrasound-Guided Hepaticocolonostomy Through the Reconstructed Colon 2026/02
8.	Original article	Intraductal Papillary Mucinous Neoplasm and Pancreatic Cancer: Opportunity Knocks Twice 2026/02
9.	Other	Response 2026/02
10.	Original article	Three-dimensional volume estimates of pancreatic fluid collections in relation to clinical outcomes of endoscopic ultrasound-guided treatment 2026/02
11.	Original article	Clinical Characteristics of Late-Onset (≥ 65 Years) Ulcerative Colitis: A Single-Center Retrospective Study 2026/01
12.	Original article	Clinical Practice Guidelines for Pancreatic Cancer 2025 From the Japan Pancreas Society: A Synopsis 2026/01
13.	Original article	Endoscopic approach to indeterminate biliary strictures 2026/01
14.	Original article	Mortality and cancer risk in patients with chronic pancreatitis in japan: insights into the importance of surveillance for pancreatic cancer 2026/01
15.	Other	Response 2026/01
16.	Original article	Current treatment strategy for asymptomatic bile duct stones 2025/12
17.	Original article	Encapsulation levels rather than elapsed time after the onset of acute pancreatitis are related to clinical outcomes of pancreatic walled-off necrosis 2025/12
18.	Other	Reply to Ancil et al 2025/12
19.	Other	Response 2025/12
20.	Other	Response 2025/11
21.	Original article	Tasurgratinib (E7090) for cholangiocarcinoma with fibroblast growth factor receptor 2 fusions/rearrangements: a multicenter, open-label, Phase 2 study 2025/11
22.	Original article	Extrahepatic Events in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease and the Impact of Genetics and Alcohol Intake 2025/10
23.	Review article	The 2024 diagnostic criteria for primary sclerosing cholangitis 2025/10
24.	Original article	Relationship of Intrapancreatic Fat Deposition With Pancreatic Cancer Differs According to Carcinoma Types 2025/09
25.	Original article	Predicting the risk of developing diabetes in steatotic liver disease using controlled attenuation parameter in a health checkup population 2025/08
26.	Original article	Efficacy and safety of a novel multi-hole fully covered self-expandable metallic stent for malignant distal biliary obstruction: Multicenter retrospective study. 2025/07
27.	Original article	Quadrant, necrosis, and infection criteria for the risk stratification of walled-off necrosis: external validation using multi-institutional data 2025/07
28.	Review article	Ergonomic endoscopy - Fundamentals of ergonomics and interventions for endoscopy-related musculoskeletal disorders. 2025/06
29.	Original article	Necrosectomy and its timing in relation to clinical outcomes of EUS-guided treatment of walled-off pancreatic necrosis: a multicenter study 2025/06
30.	Review article	Fatty Pancreas: Its Potential as a Risk Factor for Pancreatic Cancer and Clinical Implications 2025/05
31.	Original article	Risk factors for pancreatic cancer in individuals with intraductal papillary mucinous neoplasms and no high-risk stigmata during up to 5 years of surveillance: a prospective longitudinal cohort study. 2025/05
32.	Original article	Role of Endoscopy in Clinical Management of Intraductal Papillary Mucinous Neoplasms 2025/05
33.	Original article	Investigation of the Clinical Remission Course in Ulcerative Colitis from Tofacitinib Induction to Tapering or Withdrawal in Japanese Patients: A Single-Center Retrospective Study 2025/04
34.	Original article	Association between homologous recombination deficiency and time to treatment failure to platinum-based chemotherapy for pancreatic cancer by using the C-CAT database 2025/02
35.	Review article	Development of a Dedicated X-Ray Fluoroscopic Apparatus for Therapeutic Pancreatobiliary Endoscopy: A Review 2025/02
36.	Original article	Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease 2025/02
37.	Other	Can Endoscopic Ultrasound-guided Ablation Prolong Disease-specific Survival In Pancreatic Cysts? 2025/01
38.	Original article	Controversies in endoscopic ultrasonography-guided management of walled-off necrosis 2025/01
39.	Original article	Safety and Effectiveness of Colonic Stenting for Ileocecal Valve Obstruction and Usefulness of Two-Step Strategy: Single-Center Retrospective Study 2025/01
40.	Original article	Importance of gamma-glutamyl transferase elevation in patients with Fontan-associated liver disease 2024/12
41.	Other	Pancreatic Cysts 2024/11
42.	Original article	Who benefits from long-term plastic stents after walled-off necrosis treatment: prix fixe for all or à la carte? 2024/11
43.	Review article	Disconnected pancreatic duct syndrome: diagnostic and therapeutic challenges and future directions 2024/10
44.	Other	The updated Asia-Pacific consensus statement on the role of endoscopic management in malignant hilar biliary obstruction 2024/09
45.	Original article	Dedicated Echoendoscope for Interventional Endoscopic Ultrasound: Comparison with a Conventional Echoendoscope 2024/05
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■ Academic conference presentation

1.	（ランチョンセミナー6）急性胆嚢炎に対する低侵襲治療の最前線：EUS-GBD の役割と位置付け（Speech） 2026/05/22
2.	BILIARY DRAINAGE USING ENDOSCOPIC ULTRASOUND AND BALLOON ENDOSCOPY FOR MALIGNANT BILIARY OBSTRUCTION IN SURGICALLY ALTERED ANATOMY CASES （Poster notice，General） 2026/05/02
3.	CLINICAL IMPACT OF INTRODUCING A LUMEN-APPOSING METAL STENT ON THE OUTCOMES OF ENDOSCOPIC ULTRASOUND-GUIDED TREATMENT OF PANCREATIC FLUID COLLECTIONS: A CALL FOR ATTENTION TO BLEEDING （Poster notice，General） 2026/05/02
4.	CLINICAL OUTCOMES OF ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE FOR POSTOPERATIVE PANCREATIC FLUID COLLECTIONS, OVERALL AND BY STENT TYPES: A MULTICENTER COHORT STUDY （Poster notice，General） 2026/05/02
5.	DISCONNECTED PANCREATIC DUCT TYPE DETERMINES LONG-TERM PANCREATIC FUNCTION AFTER EUS-GUIDED DRAINAGE OF PANCREATIC FLUID COLLECTIONS: A MULTICENTER STUDY （Poster notice，General） 2026/05/02
6.	HEAD-TO-HEAD COMPARISON OF IMMEDIATE NECROSECTOMY VS. STEP-UP APPROACH FOLLOWING ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE OF NECROTIZING PANCREATITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS （Poster notice，General） 2026/05/02
7.	MULTICENTER RETROSPECTIVE OBSERVATIONAL STUDY ON TREATMENT STRATEGIES FOR POSTOPERATIVE PANCREATIC FISTULA （Poster notice，General） 2026/05/02
8.	NATIONWIDE QUESTIONNAIRE SURVEY REVEALS PRACTICE VARIATIONS IN ENDOSCOPIC ULTRASOUND-GUIDED TREATMENT OF WALLED-OFF PANCREATIC NECROSIS BY HOSPITAL TYPES AND CASELOADS （Poster notice，General） 2026/05/02
9.	OUTCOMES OF ENDOSCOPIC TREATMENT FOR PANCREATIC FLUID COLLECTIONS IN ELDERLY PATIENTS: HIGHER MORTALITY HIGHLIGHTS THE NEED FOR INDIVIDUALIZED CARE （Poster notice，General） 2026/05/02
10.	PREDICTIVE FACTORS FOR THE ENCAPSULATION OF ACUTE NECROTIZING PANCREATITIS WITHIN 4 WEEKS OF THE DISEASE ONSET: A MULTICENTER COHORT STUDY （Poster notice，General） 2026/05/02
11.	SUBGROUP ANALYSES OF THE WONDER-02 NON-INFERIORITY TRIAL: COMPARISON OF PLASTIC AND LUMEN-APPRPOSING METAL STENTS FOR EUS-GUIDED DRAINAGE OF PANCREATIC PSEUDOCYSTS （Poster notice，General） 2026/05/02
12.	THE 3-D VOLUME OF WALLED-OFF PANCREATIC NECROSIS PREDICTS THE NEED FOR NECROSECTOMY FOLLOWING ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE （Poster notice，General） 2026/05/02
13.	THE CLINICAL RELEVANCE OF EXTRALUMINAL AIR ON THE FOLLOWING DAY OF EUS-GUIDED DRAINAGE FOR WALLED-OFF PANCREATIC NECROSIS （Poster notice，General） 2026/05/02
14.	USEFULNESS OF CA19-9 FOR EARLY DETECTION OF PANCREATIC CANCER IN BRANCH-DUCT IPMN: RESULTS FROM A MULTICENTER PROSPECTIVE SURVEILLANCE STUDY IN JAPAN （Poster notice，General） 2026/05/02
15.	“SPONGE SIGN” AS A PREDICTIVE FACTOR FOR THE REQUIREMENT OF NECROSECTOMY FOLLOWING ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE OF WALLED-OFF PANCREATIC NECROSIS （Poster notice，General） 2026/05/02
16.	Does Quality of Biliary Drainage Affect Safety and Efficacy of Chemotherapy? （Speech，General） 2026/04/02
17.	Efficacy of Combination Therapy with Biologics and Tacrolimus as Remission Induction for Refractory Ulcerative Colitis: A Retrospective Study （Poster notice，General） 2026/02/18
18.	Efficacy of Granulocyte and Monocyte Apheresis (GMA) for Pouchitis Following Colectomy in Ulcerative Colitis Patients”Abstract （Poster notice，General） 2026/02/18
19.	（International session 胆膵）Does endoscopic sphincterotomy(EST) with balloon dilation(ESBD) have advantages over EST for small bile duct stones？（Speech，Panelist at Symposium/Workshop (Other)） 2025/12/13
20.	（International session 胆膵）Nationwide Study of LAMS Implementation for EUS-Guided Drainage of Pancreatic Fluid Collections （Speech，Panelist at Symposium/Workshop (Other)） 2025/12/13
21.	The “Difficult” ERCP – Precut or EUS? （Speech，General） 2025/12/05
22.	（EUS-TAP Masterclass　Session 2: The Next Decade of EUS）New and emerging devices （Speech，Panelist at Symposium/Workshop (Other)） 2025/11/18
23.	（Networking, Career Growth, and Leadership for Women in GI: Asia-Pacific Perspectives　Career track options: making the right choice）Elevating your academic career （Speech，Panelist at Symposium/Workshop (Other)） 2025/11/18
24.	（Problem solving in PB Endoscopy）Trouble-shooting in EUS Biliary Therapy （Speech，General） 2025/11/18
25.	（WEO Research Symposium）Preventing and Managing Musculoskeletal Injuries in Endoscopy （Speech，Panelist at Symposium/Workshop (Other)） 2025/11/18
26.	CHARACTERISTICS AND CLINICAL COURSE OF FONTANASSOCIATED LIVER DISEASE(FALD) （Poster notice，General） 2025/11/07
27.	EUS-guided tissue acquisition for solid pancreatic lesions: Does the size still matter in the era of fine needle biopsy? （Poster notice，General） 2025/10/25
28.	Is a new 3-prong asymmetric tip needle useful for the diagnosis of solid pancreatic lesions? （Poster notice，General） 2025/10/25
29.	Technical tips to increase diagnostic yield of EUS-TA （Speech，General） 2025/10/25
30.	A multicenter comparative analysis of nasocystic tube placement versus no nasocystic tube placement for endoscopic ultrasound-guided drainage of a pancreatic pseudocyst: The WONDERFUL study group in Japan （Speech，General） 2025/09/05
31.	Three-dimensional Volume Estimates of Pancreatic Fluid Collections in Relation to Clinical Outcomes of Endoscopic Ultrasound-guided Treatment. （Speech，General） 2025/09/05
32.	（Luncheon Seminar5）Interventional EUS: Future and Past （Speech） 2025/09/05
33.	Optimizing Safety and Effecacy in Endoscopic Papillectomy: Practical Techniques and pearls （Speech，General） 2025/08/01
34.	EUS guided intervention in postoperative pancreatic leaks and fistulas （Speech，General） 2025/06/21
35.	EUS-BD for right IHDs(CDS & Bridging) （Speech，General） 2025/06/21
36.	Tips for EUS-guided pancreaticgastrostomy （Speech，General） 2025/06/21
37.	（シンポジウム1　Current status and future perspectives of AI in gastrointestinal endoscopy）Development of Computer-Aided Detection for Pancreatic Tumors and Parenchyma During Endoscopic Ultrasonography （Speech，Panelist at Symposium/Workshop (Other)） 2025/05/09
38.	ASSOCIATIONS BETWEEN COMPUTED TOMOGRAPHY-BASED 3-D VOLUME OF PANCREATIC FLUID COLLECTIONS AND CLINICAL OUTCOMES OF ENDOSCOPIC ULTRASOUND-GUIDED TREATMENT: THE WONDERFUL STUDY GROUP IN JAPAN （Poster notice，General） 2025/05/03
39.	DIAGNOSTIC UTILITY OF BILE IGG4 IN DIFFERENTIATING IGG4-ASSOCIATED SCLEROSING CHOLANGITIS FROM SIMILAR HEPATOBILIARY DISEASES: A MULTICENTER STUDY （Speech，General） 2025/05/03
40.	FATTY PANCREAS AND PANCREATIC CANCER RISK IN PATIENTS WITH INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS （Poster notice，General） 2025/05/03
41.	IMMEDIATE NECROSECTOMY VS. DRAINAGE-ORIENTED STEP-UP APPROACH AFTER ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE OF WALLED-OFF NECROSIS—SUBGROUP ANALYSES OF A MULTICENTER RANDOMISED CONTROLLED TRIAL (WONDER-01) （Speech，General） 2025/05/03
42.	PLASTIC STENTS MAY PROVIDE COMPARABLE OUTCOMES TO A LUMEN-APPOSING METALLIC STENT IN PATIENTS RECEIVING ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE: MULTICENTER ANLYSIS BY THE WONDERFUL STUDY GROUP IN JAPAN （Poster notice，General） 2025/05/03
43.	PLASTIC STENTS VS. LUMEN-APPOSING METAL STENT FOR ENDOSCOPIC ULTRASOUND-GUIDED DRAINAGE OF PANCREATIC PSUEDOCYSTS: A MULTICENTER, RANDOMISED CONTROLLED, NONINFERIORITY TRIAL (WONDER-02) （Poster notice，General） 2025/05/03
44.	RISK FACTORS FOR ENDOSCOPIC MANAGEMENTS OF PANCREATIC FLUID COLLECTIONS IN PATIENTS ON ANTITHROMBOTIC THERAPY: A MULTICENTER ANALYSIS FROM THE WONDERFUL STUDY GROUP IN JAPAN （Poster notice，General） 2025/05/03
45.	RISK FACTORS FOR PANCREATIC CANCER IN INDIVIDUALS WITH INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS AND NO HIGH-RISK STIGMATA DURING UP TO FIVE YEARS OF SURVEILLANCE: A PROSPECTIVE LONGITUDINAL COHORT STUDY （Poster notice，General） 2025/05/03
46.	VARIATIONS IN SUPPORTIVE TREATMENT STRATEGIES DURING ENDOSCOPIC MANAGEMENT OF PANCREATIC FLUID COLLECTIONS: NATIONWIDE QUESTIONNAIRE SURVEY BY THE WONDERFUL STUDY GROUP IN JAPAN （Poster notice，General） 2025/05/03
47.	（シンポジウム15　急性膵炎・慢性膵炎診療の現状と今後の展望）Questionnaire Survey on Endoscopic Treatment Strategies for Pancreatic Fluid Collections in Japan：the WONDERFUL study group （Speech，Panelist at Symposium/Workshop (Other)） 2025/04/24
48.	（APBA Symposium1　Pioneering Innovations and Evolving Paradigms in EUS）EUS-guided biliary drainage as a primary technique （Speech，Panelist at Symposium/Workshop (Other)） 2025/04/04
49.	Characteristics of patients with very late-onset ulcerative colitis: A single-center retrospective study （Poster notice，General） 2025/02/19
50.	(Interventional EUS)How to Choose Between ERCP and EUS-BD for Malignant Biliary Obstruction? （Speech，General） 2025/01/11
51.	（ERCP）Case2：Operator （Speech） 2025/01/11
52.	（[The 8th Joint Session　between KDDW-TDDWJDDW]Pancreatobiliary：Latest advances in endoscopic/EUS-guided diagnosis and treatment for pancreatobiliary tumor）EUS-guidedbiliary drainage for malignant biliary osdtruction （Speech，Panelist at Symposium/Workshop (Other)） 2024/11/14
53.	（Symposium 32：Endoscopic treatment of chronic pancreatitis）Update on managemant of pancreatis duct stones （Speech，Panelist at Symposium/Workshop (Other)） 2024/11/14
54.	（Session3：Optimizing the management of cholangiocarcinoma I）Advanced pre-operative endoscopic biliary drainage for cholangiocarcinoma （Speech，General） 2024/10/18
55.	（Session5：Roadmap to improved outcomes in pancreatic cancer management I）Advanced pre-operative endoscopic biliary drainage for pancreatic cancer （Speech，General） 2024/10/18
56.	（SessionVI　EUS-guided Drainage）How to reduce complications during biliopancreatic drainage （Speech，General） 2024/10/12
57.	Dedicate biliary plastic stent－inside stent/Q&A （Speech，General） 2024/07/20
58.	（Symposium401　Cutting edge of endoscopic management of malignant biliary strictures）Next step for inclusive result of ERCP guided transpapillary tissue sampling （Speech，Panelist at Symposium/Workshop (Other)） 2024/07/04
59.	（Symposium406　Debate session on EUS intervention (Session2)）Roux-en-Y anatomy after surgery: Balloon enteroscope assisted ERCP （Speech，Panelist at Symposium/Workshop (Other)） 2024/07/04
60.	（WEO International School of EUS(WISE) session Part1）EUS-guided Biliary Drainage,Current Status （Speech，General） 2024/07/04
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■ Education

1.	2002/04～2008/03	〔Doctoral course〕〔Doctorial Course〕, Graduate School, Division of Medical Sciences, The University of Tokyo, Completed
2.	1992/04～1998/03	Faculty of Medicine, The University of Tokyo, Graduated