Faculty Information - Ishii Yasuo

■ Books

1.

Chapter contribution　

Multiple Roles for SOX2 in Eye Development., Sox2: Biology and Role in Development and Disease 2015/11

■ Published papers

1.	Original article	Wnt signal-dependent antero-posterior specification of early-stage CNS primordia modeled in EpiSC-derived neural stem cells. 2023
2.	Review article	Epiblast cells gather onto the anterior mesendoderm and initiate brain development without the direct involvement of the node in avian embryos: Insights from broad-field live imaging. 2022/10/05
3.	Original article	Live imaging of avian epiblast and anterior mesendoderm grafting reveals the complexity of cell dynamics during early brain development. 2022/03
4.	Original article	Modeling early stages of endoderm development in epiblast stem cell aggregates with supply of extracellular matrices. 2020/05/08
5.	Original article	The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components 2020/02/07
6.	Original article	Intrinsic lens potential of neural retina inhibited by Notch signaling as the cause of lens transdifferentiation. 2017/01
7.	Original article	Temporal dissociation of developmental events in the chick eye under low temperature conditions. 2016/12
8.	Original article	Chx10 functions as a regulator of molecular pathways controlling the regional identity in the primordial retina. 2016/05
9.	Original article	An anteroposterior wave of vascular inhibitor downregulation signals aortae fusion along the embryonic midline axis. 2010/11
10.	Original article	BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heart. 2010/08
11.	Original article	Eph regulates dorsoventral asymmetry of the notochord plate and convergent extension-mediated notochord formation. 2010
12.	Original article	Morphogenesis and cytodifferentiation of the avian retinal pigmented epithelium require downregulation of Group B1 Sox genes. 2009/08
13.	Review article	Endothelial cell lineages of the heart. 2009/01
14.	Original article	The surface ectoderm of the chick embryo exhibits dynamic variation in its response to neurogenic signals. 2009
15.	Original article	Induction of proepicardial marker gene expression by the liver bud. 2007/10
16.	Original article	VEGF family members regulate myocardial tubulogenesis and coronary artery formation in the embryo. 2006/04
17.	Review article	Somatic transgenesis in the avian model system. 2005/03
18.	Review article	Induction and patterning of the primitive streak, an organizing center of gastrulation in the amniote. 2004/03
19.	Review article	Somatic transgenesis using retroviral vectors in the chicken embryo. 2004/03
20.	Original article	Pax6 controls the expression of Lewis x epitope in the embryonic forebrain by regulating alpha 1,3-fucosyltransferase IX expression. 2002/01
21.	Original article	Pre-gut endoderm of chick embryos is regionalized by 1.5 days of development. 2002/01
22.	Original article	cSox3 expression and neurogenesis in the epibranchial placodes. 2001/09
23.	Original article	Sox3 expression defines a common primordium for the epibranchial placodes in chick. 2001/08
24.	Original article	Demarcation of early mammalian cortical development by differential expression of fringe genes. 2000/02
25.	Original article	Region-specific expression of chicken Sox2 in the developing gut and lung epithelium: regulation by epithelial-mesenchymal interactions. 1998/12
26.	Original article	Developmental changes in mucosubstances revealed by immunostaining with antimucus monoclonal antibodies and lectin staining in the epithelium lining the segment from gizzard to duodenum of the chick embryo. 1998/11
27.	Original article	Sonic hedgehog expression in developing chicken digestive organs is regulated by epithelial-mesenchymal interactions. 1998/02
28.	Original article	Early specification of intestinal epithelium in the chicken embryo: a study on the localization and regulation of CdxA expression. 1997/10
29.	Original article	Spatial expression of Sonic hedgehog in the lung epithelium during branching morphogenesis. 1996/08
30.	Original article	Analysis of mesenchymal influence on the pepsinogen gene expression in the epithelium of chicken embryonic digestive tract. 1996
31.	Original article	Localization of DNA-synthesizing cells and cell proliferation pattern in developing proventricular (glandular stomach) epithelium of embryonic and hatched chicken. 1996
32.	Original article	Mucus-associated antigen in epithelial cells of the chicken digestive tract: Developmental change in expression and implication for morphogenesis-function relationship. 1996
33.	Original article	Mesenchymal regulation of epithelial gene expression in developing avian stomach: 5'-flanking region of pepsinogen gene can mediate mesenchymal influence on its expression. 1994/12
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■ Academic conference presentation

1.	The expression of EphA and ephrinA family genes in the avian digestive tract. 2020/12/05
2.	Spatiotemporal control of the epicardium formation in the developing chick heart 2018/06/23
3.	VEGF-A misexpression in the epicardium of the avian heart results in connective tissue hyperplasia and ectopic vascular development 2017/05/10
4.	Epicardial misimpression of VEGF-A ectopically activates a program of vascular development 2016/10/24
5.	Multiple developmental timers coordinate vertebrate organ morphogenesis. 2015/06/03

■ Research areas

Developmental biology

■ Awards & honors

1.	2006/10	Cardiovascular Research Institute, University of California San Francisco CVRI Retreat Best Poster Award (Pigmented retina differentiation requires SoxB1 downregulation in chick)
2.	2005/05	The 11th Annual Weinstein Cardiovascular Development Conference Organizing Committee The 11th Annual Weinstein Cardiovascular Development Conference Travel Award (Induction of the Proepicardium)

■ Education

1.

1995/04～1998/03

〔Doctoral course〕 Biology, Graduate School, Division of Natural Science, Tokyo Metropolitan University, Completed,

■ Academic & professional experience

1.	2020/05～	Lecturer
2.	2016/04～2020/05	Tokyo Women's Medical University, School of Medicine Lecturer
3.	2010/04～2016/03	Kyoto Sangyo University Faculty of Life Sciences, Department of Molecular Biosciences
4.	2009/06～2010/03	University of California, San Francisco Cardiovascular Research Institute Associate Specialist
5.	2006/04～2009/05	University of California, San Francisco Cardiovascular Research Institute Postdoctoral Scolar
6.	2005/06～2006/03	Weill Medical College, Cornell University Department of Cell & Developmental Biology Research Associate
7.	2003/06～2005/05	Weill Medical College, Cornell University Department of Cell & Developmental Biology Postdoctoral Associate
8.	1999/11～2002/11	The University of Nottingham Institute of Genetics Research Associate
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