Faculty Information

（Last updated : 2025-05-02 09:54:09）

INAI Kei
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Surgery, Division of Pediatric Cardiology and Adult Congenital Cardiology

Position Associate Professor

■ Published papers

1.	Case report	Histological investigation of persistent fifth aortic arch with arch obstruction in a neonate 2025/05/01
2.	Original article	Impact of ursodeoxycholic acid treatment on Fontan-associated liver disease 2025/02
3.	Original article	Importance of gamma-glutamyl transferase elevation in patients with Fontan-associated liver disease 2024/12
4.	Original article	Abdominal lymphatic pathway in Fontan circulation using non-invasive magnetic resonance lymphangiography. 2023/04
5.	Other	Ventricular assist device for end-stage adult congenital heart disease patients: Current status. 2023/04
6.	Original article	Hepatocellular carcinoma and focal nodular hyperplasia in patients with Fontan-associated liver disease: characterisation using dynamic gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced MRI. 2023/03
7.	Original article	Predictors of long-term mortality among perioperative survivors of Fontan operation. 2022/07/01
8.	Original article	Surgical outcomes of reoperation after Fontan completion 2022/02/21
9.	Original article	Management of pregnancy and delivery in women with transposition of the great arteries after atrial switch operation: A 16-year single-center experience. 2022/02
10.	Original article	Risk factors for Fontan-associated hepatocellular carcinoma. 2022/01
11.	Original article	Incidence and Expected Probability of Liver Cirrhosis and Hepatocellular Carcinoma After Fontan Operation. 2021/12
12.	Original article	Skeletal muscle index determined by bioelectrical impedance analysis is a determinant of exercise capacity and a prognostic predictor in patients with congenital heart disease. 2020/05
13.	Original article	Clinical Significance of Central Venous Pressure During Exercise After Fontan Procedure. 2020/02
14.	Original article	Predictors of neo-aortic valve regurgitation in the long term after arterial switch operation 2020
15.	Original article	Liver Strain Using Feature Tracking of Cine Cardiac Magnetic Resonance Imaging: Assessment of Liver Dysfunction in Patients with Fontan Circulation and Tetralogy of Fallot. 2019/12
16.	Original article	Feature-Tracking MRI Fractal Analysis of Right Ventricular Remodeling in Adults with Congenitally Corrected Transposition of the Great Arteries Radiology. 2019/10
17.	Original article	The relationship between extracellular volume fraction in symptomatic adults with tetralogy of Fallot and adverse cardiac events. 2019/10
18.	Original article	Clinical impact of cardiac computed tomography derived three-dimensional strain for adult congenital heart disease: a pilot study. 2019/08
19.	Original article	Prevalence and risk factors of sleep apnea in adult patients with congenital heart disease. 2019/05
20.	Original article	Bioelectrical impedance analysis in the management of heart failure in adult patients with congenital heart disease. 2019/03
21.	Original article	Global strain and dyssynchrony of the single ventricle predict adverse cardiac events after the Fontan procedure: Analysis using feature-tracking cine magnetic resonance imaging. 2019/02
22.	Original article	Mode of death and predictors of mortality in adult Fontan survivors: A Japanese multicenter observational study. 2019/02
23.	Original article	Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension. 2019/01
24.	Original article	Stroke volume ratio derived from magnetic resonance imaging as an indicator of interventricular dyssynchrony predicts future cardiac event in patients with biventricular Fontan circulation. 2019/01
25.	Original article	Inter- and intra-ventricular dyssynchrony in the systemic right ventricle is a surrogate marker of major cardiac events in mildly symptomatic patients. 2018/09
26.	Original article	Prediction of Fontan-Associated Liver Disease Using a Novel Cine Magnetic Resonance Imaging "Vortex Flow Map" in the Right Atrium. 2018/07
27.	Original article	Influence of pregnancy on cardiac function and hemodynamics in women with Ebstein's anomaly. 2018/05
28.	Original article	Pregnancy and delivery outcomes from patients with repaired anomalous origin of the left coronary artery from the pulmonary artery. 2018/05
29.	Original article	Vortex Flow in the Right Atrium Surrogates Supraventricular Arrhythmia and Thrombus After Atriopulmonary Connection-Type Fontan Operation: Vortex Flow Analysis Using Conventional Cine Magnetic Resonance Imaging. 2018/02
30.	Original article	Clinical implications of eicosapentaenoic acid/arachidonic acid ratio (EPA/AA) in adult patients with congenital heart disease. 2017/12
31.	Original article	Outcomes from anomalous origin of the left coronary artery from the pulmonary artery repair: Long-term complications in relation to residual myocardial abnormalities. 2017/11
32.	Original article	Significance of right atrial tension for the development of complications in patients after atriopulmonary connection Fontan procedure: potential indicator for Fontan conversion. 2017/07
33.	Original article	Prognostic predictive value of gene mutations in Japanese patients with hypertrophic cardiomyopathy. 2017/06
34.	Original article	Long-term Outcomes after Truncus Arteriosus Repair: A Single-center Experience for More than 40 Years. 2016/12
35.	Original article	Prognostic value of multiple biomarkers for cardiovascular mortality in adult congenital heart disease: comparisons of single-/two-ventricle physiology, and systemic morphologically right/left ventricles 2016/11
36.	Original article	Blood coagulation abnormalities and the usefulness of D-dimer level for detecting intracardiac thrombosis in adult Fontan patients 2016/09
37.	Original article	Risk factors and serological markers of liver cirrhosis after Fontan procedure. 2016/09
38.	Original article	Outcomes in children with advanced heart failure in Japan: importance of mechanical circulatory support. 2016/07
39.	Original article	High prevalence of cardiovascular risk factors in children and adolescents with Williams-Beuren syndrome. 2015/09
40.	Original article	Relationships among red cell distribution width, anemia, and interleukin-6 in adult congenital heart disease. 2015/05
41.	Original article	Mutations of NOTCH3 in childhood pulmonary arterial hypertension. 2014/05
42.	Original article	Survey of the current status and management of Eisenmenger syndrome: A Japanese nationwide survey. 2014/04
43.	Original article	Soluble ST2 and N-terminal pro-brain natriuretic peptide combination-Useful biomarker for predicting outcome of childhoodpulmonary arterial hypertension- 2014/02
44.	Other	Aortic Dilatation (AD) and Bentall Operation in Tetralogy of Fallot (TOF) 2010
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■ Academic conference presentation

1.	Identification of PTGIS variants in patients with Williams syndrome and severe peripheral pulmonary stenosis （口頭，一般） 2024/10/12
2.	Platelet volume indices correlate to severity of heart failure and have prognostic value for both cardiac and thrombotic events in patients with congenital heart disease （ポスター掲示，一般） 2020/08/29
3.	Usefulness of 3DCT in ACHD （口頭） 2020/01/19
4.	Maternal and fetal outcomes in pregnant woman with surgically repaired congenital heart disease: retrospective Japanese multi-center study （口頭，シンポジウム・ワークショップパネル（その他）） 2019/06/28
5.	Women with Fontan Circulation （口頭，シンポジウム・ワークショップパネル（公募）） 2019/04/19
6.	APC Fontan -Long term outcome and timing of TCPC conversion- （口頭） 2019/04/06
7.	Bioelectrical impedance parameters are determinants for exercise capacity in the patients with adult congenital heart disease （ポスター掲示，一般） 2018/08/26
8.	Relationship of Myocardial Perfusion SPECT Defect Score and Patients with Fontan Procedure （口頭，一般） 2018/03/25
9.	Intrarenal Hemodynamics Evaluation by Doppler Ultrasonography in Fontan Patients. （ポスター掲示，一般） 2018/03/23
10.	Skeletal Muscle Mass Determined by Bioelectrical Impedance Analysis is Associated With Exercise Capacity and Cardiac Events in Patients With Congenital Heart Disease （口頭，一般） 2017/11/13
11.	Energy-loss in fontan circulation develops heterogeneous pulmonary perfusion: hybrid analysis of 2D vortex flow map and 4D flow MRI. （ポスター掲示，一般） 2017/04/24
12.	Can Hemodynamics Parameter after First Palliative Operation Predict Hemodynamics after Fontan Procedure? （ポスター掲示，一般） 2017/03/19
13.	Prediction of Liver Congestion after Fontan Operation Using Vortex Flow Map of Cardiac Cine MR Imaging （ポスター掲示，一般） 2017/03/19
14.	Long-Term Outcomes of the Fontan Operation: Forty Years of Experience at a Single Institute （口頭，一般） 2017/03/18
15.	Relationship of Myocardial Perfusion Defect and Dysfunctional Systemic Right Ventricle in Congenital or Surgical Corrected Transposition of the Great Arteries （ポスター掲示，一般） 2017/03/18
16.	Fontan Palliation with a Biventricular Heart Has Potential Ventricular Deterioration Depending on Dominant Ventricular Characters （ポスター掲示，一般） 2017/03/17
17.	Impact of Pregnancy in Patients with a Systemic Right Ventricle （ポスター掲示，一般） 2017/03/17
18.	Vortex Flow Surrogates Arrhythmia and Thrombus after APC Fontan: Novel Method of Vortex Flow Analysis Using Conventional Cine MRI （ポスター掲示，一般） 2017/03/17
19.	Efficacy of expandable hydrogel polymer coil embolization for aortopulmonary collateral artery. （口頭，一般） 2017/01/28
20.	Novel technique of penetration for tough obstractive lesions. （口頭） 2017/01/27
21.	Fontan Palliation with a Biventricular Heart has Potential Ventricular Deterioration Depending on Dominant Ventricular Characters （口頭，一般） 2017/01/15
22.	Interventricular dyssynchrony is associated with cardiac dysfunction and New York Heart Association classes in Fontan circulation with biventricular heart （ポスター掲示，一般） 2017/01/15
23.	The marker for platlet activation in adult patients with congenital heart disease （ポスター掲示，一般） 2017/01/15
24.	Vortex flow in the right atrium is associated with low voltage area and supraventricular tachycardia after Fontan operation.- A study of novel imaging method, "vortex flow map"- （ポスター掲示，一般） 2017/01/15
25.	Vortex flow in the right atrium surrogates supraventricular arrhythmia and thrombus after atrio-pulmonary connection type Fontan operation: a novel method of vortex flow analysis using conventional cine magnetic resonance imaging （口頭，一般） 2017/01/15
26.	Bioelectrical Impedance Analysis Is Useful For The Management Of Heart Failure And Prediction Of Cardiac Events In Adult Patients With Congenital Heart Disease （ポスター掲示，一般） 2016/11/14
27.	Transcatheter closure for ASD with pulmonary hypertension （口頭，一般） 2016/01/29
28.	The Effects of Cardiac Resynchronization Therapy Using Transvenous Approach on Clinical Outcome in Patients with Systemic Right Ventricle Failure （口頭，一般） 2015/04/26
29.	Clinical Implication of Serum TGF-b Levels in Patients with Fontan Physiology （ポスター掲示，一般） 2015/04/25
30.	A case of polysplenia complicated with pulmonary hypertension and extrahepatic portosystemic shunt （ポスター掲示，一般） 2015/01/18
31.	A case report that was able to give birth after David operation for Marfan syndrome complicated with annuloaortic ectasia. （ポスター掲示，一般） 2015/01/18
32.	Influence on cardiac function after the delivery in postoperative Bland-White-Garland syndrome patients. （ポスター掲示，一般） 2015/01/18
33.	Protein-losing enteropathy(PLE) after the Fontan operation: Hemodynamics and treatment strategy （口頭，一般） 2015/01/17
34.	Clinical Significance of Impaired Vascular Endothelial Function in Patients After Fontan Procedure. （ポスター掲示，一般） 2014/11/19
35.	Factors Associated with Glucose Intolerance and Abnormal Lipid Metabolism in Fontan Patients. （ポスター掲示，一般） 2014/11/16
36.	Prognostic Value of Multiple Biomarkers on Mortality in Adults Congenital Heart Disease: Comparison of Single- and Two-Ventricle Physiology. （ポスター掲示，一般） 2014/11/16
37.	The importance of right atrium tension in patients after atriopulmonary Fontan procedure （ポスター掲示，一般） 2014/05/23
38.	Seeking the Ideal Cooperative Structure with Multidisciplinary Experts for Adult Patients with Congenital Heart Disease （口頭，シンポジウム・ワークショップパネル（その他）） 2014/03/21
39.	Genotype-phenotype relationship of idiopathic cardiomyopathy in childhood （ポスター掲示，一般） 2014/03/08
40.	Sildenafil Reduces Pulmonary Vascular Resistance in Patients With Single Ventricular Physiology （口頭，一般） 2013/11/20
41.	Ten, 20, and 30-Year Outcomes of Patients After Fontan Operation （ポスター掲示，一般） 2013/11/20
42.	Venous Flow Dynamics Rather Than Venous Pressure is Important for the Development of Liver Fibrosis After Atriopulmonary Fontan Procedure （ポスター掲示，一般） 2013/11/20
43.	Clinical Outcomes of Mutation Carriers in Pulmonary Arterial Hypertension in Children （ポスター掲示，一般） 2012/11/07
44.	Up to 39 Year's of Follow-up After Repair of Truncus Arteriosus （ポスター掲示，一般） 2012/11/07
45.	Exercise Physiology and Determinants of Exercise Capacity in Patients With Fontan Circulation （口頭，一般） 2012/11/06
46.	Double Gene Mutations in Long QT Syndrome Can Cause Significantly Increased Cardiac Event During Childhood （ポスター掲示，一般） 2012/11/04
47.	Vitamin D kinetics and parathyroid function in patients with congenital heart disease （ポスター掲示，一般） 2012/05/23
48.	Clinical Impact of the Lung Function in Adult Patients Late after Fontan Operation （口頭，一般） 2012/04/06
49.	Thrombolitic Event and Anticoagulant Therapy Long after the Fontan Operation （ポスター掲示，一般） 2012/03/17
50.	Daily Physical Activity in Patients After a Fontan Operation Improves Functional Capacity,Which is Related to Endothelial Function and Skeletal Muscle Hemodynamics （口頭，一般） 2011/11/16
51.	Clinical Features of Compound and Double Mutations in Patients with Hypertrophic Cardiomyopathy （ポスター掲示，一般） 2011/08
52.	The cardio renal anemia syndrome in adult patients with congential heart disease （一般） 2011/05/18
53.	The Clinical implication of serum uric acid levels in adult patients with congenital heart disease （ポスター掲示，一般） 2011/05/18
54.	Aortic Dilatation (AD) and Bentall Operation in Tetralogy of Fallot (TOF) （一般） 2010/07
55.	Plasma fibrinogen level is associated with endothelial function and hemodynamics in the working skeletal muscle in patients after the Fontan operation （一般） 2009/06
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■ Social activities

2020/01

(Chairperson) Symposium2 Pathophysiology and Management of Fontan Failure in the Era of Extracardiac TCPC/The 22nd Annual Meeting of the Japanese Society for Adult Congenital Heart Disease

■ Education

1.	2009/03/27 Degree Acquisition	Tokyo Women's Medical University, PhD
2.	1983/04～1989/03	Faculty of Medicine, University of Tsukuba, Graduated,