Faculty Information - OKAMOTO Yuuko

（Last updated : 2025-06-20 23:04:38）

OKAMOTO Yuuko
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Department of Internal Medicine, Division of Rheumatology

Position Assistant Professor

■ Published papers

1.	Original article	Rheumatoid arthritis development and survival in idiopathic interstitial pneumonia patients with anti-citrullinated protein antibodies. 2025/07
2.	Original article	Expansion of HLA-DR Positive Peripheral Helper T and Naive B Cells in Anticitrullinated Protein Antibody-Positive Individuals At Risk for Rheumatoid Arthritis. 2024/07
3.	Other	Reply. 2022/03/18
4.	Original article	Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis. 2022/01/01
5.	Original article	Validation of the Japanese version of the Lupus Damage Index Questionnaire in a large observational cohort: A two-year prospective study. 2021/07/04
6.	Original article	Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes. 2021/02
7.	Original article	Clinical usefulness of anti-M-type phospholipase-A-receptor antibodies in patients with membranous nephropathy and the comparison of three quantification methods. 2020/03
8.	Original article	Complement and its environmental determinants in the progression of human rheumatoid arthritis. 2019/08
9.	Original article	Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction. 2018/09
10.	Original article	Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients. 2017/06
11.	Original article	A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. 2016/10
12.	Original article	Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis. 2016/10
13.	Original article	Validation of the Japanese version of the Systemic Lupus Activity Questionnaire that includes physician-based assessments in a large observational cohort. 2016/04
14.	Original article	Serum antibodies against the 70k polypeptides of the U1 ribonucleoprotein complex are associated with psychiatric syndromes in systemic lupus erythematosus: a retrospective study. 2013/01
15.	Original article	Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis. 2012/09
16.	Original article	Clinical manifestations of neurological involvement in primary Sjögrens syndrome. 2011/04
17.	Original article	Interleukin-18 is a key mediator in dermatomyositis: potential contribution to development of interstitial lung disease. 2010/10
18.	Original article	Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis. 2010/09
19.	Original article	Clinical images: Dramatic amelioration of pneumatosis cystoides intestinalis in systemic sclerosis. 2010/04
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■ Academic conference presentation

1.	Association of Soluble Immune Checkpoint Proteins with the Risk of Developing RA in ACPA-positive At-risk Individuals （Poster notice，General） 2024/11/16
2.	Flow Cytometry of Cells Within Induced Sputum from Individuals At-Risk for RA Reveals Relative Expansion of Small Macrophages （Poster notice，General） 2024/11/16
3.	Serum From Patients with SLE And Anti-MDA5 Antibody Positive Dermatomyositis Induce Shared Monocyte Cytokine Signature Through Type 1 （Poster notice，General） 2022/11/13
4.	Analysis Of Relationship Between Clinical Manifestations and Autoantibody Profile In ISN/RPS Class V Lupus Nephritis （Poster notice，Panelist at Symposium/Workshop (Appointed)） 2013/10
5.	Pirfenidone and BIBF1120 Suppress Collagen Synthesis In Skin Fibroblast From Patients With Systemic Sclerosis （Poster notice，General） 2013/10
6.	line blot assay (LBA), a screening test for autoantibodies in systemic sclerosis (SSc) （Poster notice，General） 2012/11
7.	Urinary λ Free Light Chain Concentration Is Associated with Disease Activity and Response to Treatment in Proliferative Lupus Nephritis （Poster notice，General） 2011/11
8.	Anti-C1q Antibodies Are Associated with Global Activity of Systemic Lupus Erythematosus, but Not Specifically with Nephritis. （Poster notice，General） 2010/11/09
9.	Predominant Suppression of Plasmablasts by Cyclophosphamide in Patients with Systemic Lupus Erythematosus: A Possible Therapeutic Mechanism. （Poster notice，General） 2010/11/09
10.	Association of Low-dose Pulsed Intravenous Cyclophosphamide Therapy and Amenorrhea in 62 patients with Systemic Lupus Erythematosus: A Case-control Study. （Poster notice，General） 2010/11/08
11.	Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis. （Poster notice，General） 2010/11
12.	Interleukin-18 is a key mediator in dermatomyositis: potential contribution to development of interstitial lung disease. （Poster notice，General） 2010/11
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■ Awards & honors

2020/04

日本リウマチ学会国際ワークショップ優秀演題賞