Faculty Information - Mochidzuki Makiko

（Last updated : 2024-06-26 11:52:15）

Mochidzuki Makiko
Department School of Medicine, School of Medicine Department of Anatomy, Division of Microscopic and Developmental Anatomy

Position Assistant Professor

■ Published papers

1.	Original article	Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells 2024/06/24
2.	Original article	Replication stress increases mitochondrial metabolism and mitophagy in FANCD2 deficient fetal liver hematopoietic stem cells 2023/03/07
3.	Original article	Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome. 2018/11
4.	Original article	The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition. 2016/07
5.	Original article	Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner. 2015/09
6.	Original article	Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice. 2015/08
7.	Original article	Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice. 2015
8.	Original article	Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development. 2014/12
9.	Original article	Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation. 2014/06
10.	Original article	The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells. 2014/02
11.	Original article	Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders. 2013/11
12.	Original article	Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. 2012/08
13.	Original article	Tumor suppressor function of the polycomb group genes. 2012/06
14.	Original article	Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes. 2012/03
15.	Original article	Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. 2011/12
16.	Original article	Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells. 2011/06
17.	Original article	Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase. 2011
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■ Education

〔Doctoral course〕, Chiba University, Completed,