■ Published papers
Original article
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1.
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Nicholson AG†, Torkko K, Viola P, Duhig E, Geisinger K, Borczuk AC, Hiroshima K, Tsao MS, Warth A, Lantuejoul S, Russell PA, Thunnissen E, Marchevsky A, Mino-Kenudson M, Beasley MB, Botling J, Dacic S, Yatabe Y, Noguchi M, Travis WD, Kerr K, Hirsch FR, Chirieac LR, Wistuba II, Moreira A, Chung JH, Chou TY, Bubendorf L, Chen G, Pelosi G, Poleri C, Detterbeck FC, Franklin WA.:
Interobserver Variation Among Pathologists And Refinement Of Criteria In Distinguishing Separate Primary Tumours From Intrapulmonary Metastases In Lung.
Journal of Thoracic Oncology
13
(2)
:205-217
, 2018.2
DOI:10.1016/j.jtho.2017.10.019.
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2.
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Rosen LE†, Karrison T, Ananthanarayanan V, Gallan AJ, Adusumilli PS, Alchami FS, Attanoos R, Brcic L, Butnor KJ, Galateau-Sallé F, Hiroshima K, Kadota K, Klampatsa A, Stang NL, Lindenmann J, Litzky LA, Marchevsky A, Medeiros F, Montero MA, Moore DA, Nabeshima K, Pavlisko EN, Roggli VL, Sauter JL, Sharma A, Sheaff M, Travis WD, Vigneswaran WT, Vrugt B, Walts AE, Tjota MY, Krausz T, Husain AN.:
Nuclear grade and necrosis predict prognosis in malignant epithelioid pleural mesothelioma: a multi-institutional study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
31
(4)
:598-606
, 2018.1
DOI:10.1038/modpathol.2017.170.
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3.
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Arimura K†, Sekine Y, Hiroshima K, Sato A, Hasegawa M, Katsura H, Tagaya E, Kondo M, Tamaoki J:
The efficacy of transbronchial needle aspiration with endobronchial ultrasonography using a guide sheath for peripheral pulmonary lesions suspected to be lung cancer.
Respiratory investigation
55
(6)
:365-371
, 2017.11
DOI:10.1016/j.resinv.2017.08.004.
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4.
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Morinaga T†, Nguyen TTT, Zhong B, Hanazono M, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M.:
An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.
Virology journal
14
(1)
:219
, 2017.11
DOI:10.1186/s12985-017-0888-0
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5.
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Kinoshita Y†, Hida T, Hamasaki M, Matsumoto S, Sato A, Tsujimura T, Kawahara K, Hiroshima K, Oda Y, Nabeshima K.:
A combination of MTAP and BAP1 immunohistochemistry in pleural effusion cytology for the diagnosis of mesothelioma.
Cancer
126
(1)
:54-63
, 2017.10
DOI:10.1002/cncy.21928
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6.
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Yamauchi S†, Zhong B, Kawamura K, Yang S, Kubo S, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M.:
Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes.
BMC cancer
17
(1)
:622
, 2017.9
DOI:10.1186/s12885-017-3621-x
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7.
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Alberto. M. Marchevsky†, Nolwenn LeStang, Kenzo Hiroshima, Giuseppe Pelosi, Richard Attanoos, Andrew Churg, Lucien Chirieac, Sanja Dacic, Aliya Husain, Andras Khoor, Sonja Klebe, Silvie Lantuejoul, Victor Roggli, Jean-Michel Vignaud, Birgit Weynand, Jennifer Sauter, M.D.16, Douglas Henderson
Kazuki Nabeshima, Francoise Galateau-Salle:
The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung. Evidence-Based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.
Human pathology
67
:160-168
, 2017.9
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8.
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Masunaga A†*, Omatsu M, Kunimura T, Uematsu S, Kamio Y, Kitami A, Miyagi Y, Hiroshima K, Suzuki T.:
Expression of PTEN and its pseudogene PTENP1, and promoter methylation of PTEN in non-tumourous thymus and thymic tumours.
Journal of clinical pathology
70
(8)
:690-696
, 2017.8
DOI:1136/jclinpath-2016-204220.
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9.
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Kengo Shimazu†, Yuji Tada, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Hideaki Shimada, Kenzo Hiroshima, Takao Namiki, Koichiro Tatsumi, Masatoshi Tagawa:
Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways.
BMC cancer
17
:309
, 2017.5
DOI:10.1186/s12885-017-3300-y
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10.
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Nguyen Canh H†, Harada K, Ouchi H, Sato Y, Tsuneyama K, Kage M, Nakano M, Yoshizawa K, Takahashi A, Abe M, Kang JH, Koike K, Inui A, Fujisawa T, Takaki A, Arinaga-Hino T, Torimura T, Suzuki Y, Fujiwara K, Zeniya M, Ohira H, Tanaka A, Takikawa H:
Acute presentation of autoimmune hepatitis: a multicenter study with detailed histological evaluation in large cohort of patients.
Journal of clinical pathology
70
(11)
:961-969
, 2017.4
DOI:10.1136/jclinpath-2016-204271
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Review article
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1.
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廣島健三†*:
中皮腫診断の新たな局面.
肺癌
57
(4)
:259-271
, 2017.8
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2.
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Kenzo Hiroshima†*, Mari Mino-Kenudson:
Update on large cell neuroendocrine carcinoma.
Translational Lung Cancer Research
6
(5)
:530-539
, 2017.6
DOI:10.21037/tlcr.2017.06.12
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3.
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中野雅行†*, 谷一郎:
細胆管細胞癌再考 -コンセプト癌ー.
肝胆膵
74
(5)
:717-723
, 2017.5
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4.
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廣島健三†, 多田裕司:
悪性中皮腫UPDATE はじめに.
医学のあゆみ
261
(2)
:127
, 2017.4
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5.
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廣島健三†:
悪性中皮腫UPDATE 中皮腫の病理診断のupdate.
医学のあゆみ
261
(2)
:150-156
, 2017.4
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6.
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廣島健三†:
病理診断に直結した組織学 漿膜.
病理と臨床
35
(臨時増刊)
:172-178
, 2017.4
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Case report
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1.
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Masunaga A†, Ishibashi F, Koh E, Oide T, Sekine Y, Hiroshima K:
Possible relationship between fibrosis of IgG4-related thymitis and the profibrotic cytokines, transforming growth factor beta 1, interleukin 1 beta and interferon gamma: a case report.
Diagnostic Pathology
13
(1)
:6
, 2018.1
DOI:10.1186/s13000-018-0684-1
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2.
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Kimura N†, Hasegawa M, Hiroshima K.:
SMARCB1/INI1/BAF47- deficient pleural malignant mesothelioma with rhabdoid features.
Pathology International
68
(2)
:128-132
, 2018.1
DOI:10.1111/pin.12623
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3.
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Oide T†*, Mitsuishi T:
Pigmented Macule - A Skin Manifestation of Invasive Breast Cancer.
The New England journal of medicine
377
:1777
, 2017.11
DOI:10.1056/NEJMicm1704791
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4.
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Oide T†*, Hiroshima K, Shibuya K, Nakatani Y.:
Primary Pulmonary Meningioma Presenting as a Coin Lesion.
Internal Medicine
56
:2073-2074
, 2017.8
DOI:10.2169/internalmedicine.56.8481.
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5.
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Hasegawa M†, Sakai F, Okabayashi A, Sato A, Yokohori N, Katsura H, Asano C, Kamata T, Koh E, Sekine Y, Hiroshima K, Ogura T, Takemura T.:
Intravenous Immunoglobulin Monotherapy for Granulomatous Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency.
Internal Medicine
56
(21)
:2899-2902
, 2017.7
DOI:10.2169/internalmedicine.7757-16
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6.
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Oide T†, Kadosono O, Matsushima J, Wu D, Nagashima H, Saigusa H, Masunaga A, Nakatani Y, Hiroshima K.:
Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma with squamous differentiation: A novel histological finding.
Human pathology
70
:43-48
, 2017.6
DOI:10.1016/j.humpath.2017.05.020
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7.
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Masunaga A†, Oide T, Kamata T, Kou E, Sekine Y, Hiroshima K.:
GLUT-1 expression of pulmonary mixed squamous cell and glandular papilloma may be associated with high SUVmax on fluorodeoxyglucose-positron emission tomography.
Pathology International
67
(7)
:373-374
, 2017.6
DOI:10.1111/pin.12547
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8.
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Oide T†*, Hiroshima K, Takahashi Y, Fugo K, Yamatoji M, Kasamatsu A, Endo-Sakamoto Y, Shiiba M, Uzawa K, Tanzawa H, Nagao T, Nakatani Y.:
Mucoepidermoid carcinoma with extensive spindled morphology and melanocytic marker expression.
Human pathology
67
:181-186
, 2017.4
DOI:10.1016/j.humpath.2017.03.010.
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9.
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Hasegawa M†*, Sakai F, Okabayashi A, Katsura H, Kamata T, Koh E, Sekine Y, Takemura T, Nakatani Y, Hiroshima K.:
Rosai-Dorfman Disease of the Lung Overlapping with IgG4-related Disease: The Difficulty in Its Differential Diagnosis.
Internal Medicine
56
(8)
:937-941
, 2017.4
DOI:10.2169/internalmedicine.56.7609
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Other
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1.
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佐藤之俊, 廣島健三, 木浦勝行, 薄田勝男, 大林千穂, 河原邦光, 桜田晃, 羽場礼次, 三浦弘之, 三窪将史, 吉澤明彦, 柿沼廣邦, 竹中明美, 三宅真司:
悪性胸膜中皮腫細胞診断の手引き.
日本肺癌学会
https
://www.haigan.gr.jp/uploads/files/photos/1539.pdf
, 2017.12
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■ Academic conference presentation
1.
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◎Kenzo Hiroshima, Di Wu, Yasuo Sekine, Daisuke Ozaki, Toshikazu Yusa, Shoutaro Tsuji, Yohei Miyagi, Aliya Husain, Kohzoh Imai:
HEG1 is a Novel Mucin-like Membrane Protein That is Useful for the Diagnosis of Malignant Mesothelioma.
USCAP 2018 Annual Meeting,
Vancouver, Canada,
2018/03
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2.
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◎Toshiaki Kawai, Koji Kameda, Hiroshi Nakashima, Kenzo Hiroshima:
Reduced expression of SMARCB1/INI1 protein in malignant mesothelioma.
USCAP 2018 Annual Meeting,
Vancouver, Canada,
2018/03
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3.
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◎Kenzo Hiroshima:
Scientific Highlights - Biology/Pathology and Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies.
IASLC 18th World Conference on Lung Cancer,
Yokohama,
2017/10
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4.
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◎Kenzo Hiroshima, Di Wu, Toshikazu Yusa, Daisuke Ozaki, Eitetsu Koh, Yasuo Sekine, Reiji Haba, Kota
Washimi, Kazuki Nabeshima, Tohru Tsujimura:
FISH Analysis of p16 and BAP1 Immunohistochemistry for the Diagnosis of Mesothelioma.
IASLC 18th World Conference on Lung Cancer,
Yokohama,
2017/10
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5.
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◎Kenzo Hiroshima, Di Wu, Zhibin Gao, Kazuki Nabeshima , Tohru Tsujimura:
Analysis of p16 deletion and loss of BAP1 in peritoneal mesotheliomas in Japan and in China.
Pulmonary Pathology Society 2017 Meeting,
Chicago, U.S.A.,
2017/06
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6.
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◎Seki R, Kawai T, Kiguchi H, Takeda T, Murakami T, Aoe K, Okabe K, Homma K, Tokunaga O, Tsukamoto Y, Sunada K, Hiroshima K:
Malignant mesothelioma with heterologous elements.
Pulmonary Pathology Society 2017 Meeting,
Chicago, U.S.A.,
2017/06
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7.
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◎Masatoshi Tagawa, Thao Th Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima:
An inhibitor for the MDM2-p53 Interaction Produces Synergistic Cytotoxicity with Oncolytic Adenoviruses on Mesothelioma with Wild-type p53 Genotype.
American Society of Gene & Cell Therapy 2017 Annual Meeting,
Washington, DC, USA,
2017/05
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8.
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◎大出貴士, 地曵典恵, 三石剛, 増永敦子, 廣島健三:
乳輪部皮膚に黒色斑を伴った乳頭部乳癌の一例.
第58回河田町乳癌研究会,
新宿,
2018/02
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9.
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◎角奈美子, 南部周平, 今野辰, 髙橋昌樹, 末澤亜紀, 黄英哲, 関根康雄, 大出貴士, 増永敦子, 廣島健三:
気管支鏡細胞診材料における肺癌の組織型推定の検討.
第56回日本臨床細胞学会秋期大会,
福岡,
2017/11
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10.
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◎廣島健三:
石綿(アスベスト)の健康影響や被害について.
平成29年度 石綿(アスベスト)健康診断・治療従事者及び相談業務担当者研修会,
千葉,
2017/11
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11.
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◎多田裕司, 田川雅敏, 新行内雅斗, 由佐俊和, 巽浩一郎, 島田英昭, 廣島健三:
10年の経過で胸郭の縮小をきたし、病理学的に中皮腫との鑑別が困難であった びまん性胸膜肥厚の1例.
第24回石綿・中皮腫研究会,
大阪,
2017/10
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12.
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◎田川雅敏, 多田裕司, 新行内雅斗, 由佐俊和, 巽浩一郎, 島田英昭, 廣島健三:
ミッドカインはメソセリンと診断的価値の異なる新たな中皮腫の予後マーカー候補である.
第24回石綿・中皮腫研究会,
大阪,
2017/10
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13.
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◎廣島健三:
新しいTNM分類(第8版)について.
第24回石綿・中皮腫研究会,
大阪,
2017/10
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14.
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◎廣島健三:
悪性中皮腫について-胸膜中皮腫を主体に-.
第12回 中皮腫細胞診セミナー,
広島,
2017/09
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15.
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◎齋藤直, 原田拓弥, 西村紘一, 瀬戸口誠, 乾政志, 増永敦子, 大出貴士, 廣島健三:
Thyroid-like follicular carcinoma of the kidneyの一例.
第82回日本泌尿器科学会東部総会,
東京,
2017/09
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16.
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◎盛永 敬郎, グエン タオ, チョン ボウヤア, 久保 秀司, 関根 郁夫, 多田 裕司, 巽 浩一郎, 島田 英昭, 廣島 健三, 田川 雅敏:
アデノウイルスによる細胞死とウイルスの複製における Wee1 キナーゼの役割.
第76回日本癌学会学術総会,
横浜,
2017/09
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17.
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◎田川雅敏, グエンダオ, 鐘博雅, 盛永敬郎, 久保秀司, 関根郁夫, 多田裕司, 巽浩一郎, 島田英昭, 廣島健三:
MDM2阻害剤 はp53野生型悪性中皮腫の内因性p53を増加させ腫瘍融解性ウイルスによる細胞傷害活性を上昇させる.
第76回日本癌学会学術総会,
横浜,
2017/09
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18.
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◎Masatoshi Tagawa, Thao Thi Thanh Nguyen, Takao Morinaga, Boya Zhong, Michiko Hanazono, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima:
A MDM2 inhibitor augments cytotoxicity of oncolytic adenoviruses defective of E1B 55kDa molecules through enhancing DNA damages and apoptosis in mesothelioma.
第23回日本遺伝子細胞治療学会,
岡山,
2017/07
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19.
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◎Takao Morinaga, Thao Thi Thanh Nguyen, Boya Zhong, Shuji Kubo, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa:
A Wee1 kinase inhibitor increases apoptosis of replication-competent adenoviruses through induction of mitotic catastrophe and enhancement of viral replications.
第23回日本遺伝子細胞治療学会,
岡山,
2017/07
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20.
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◎西村紘一, 瀬戸口誠, 齋藤直, 土岐大介, 大出貴士, 増永敦子, 梶本俊一, 乾政志:
血液透析患者に発生した膀胱原発パラガングリオーマの一例.
第62回日本透析医学会学術集会・総会,
横浜,
2017/06
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21.
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◎鍋島一樹, 木下義晃, 松本慎二, 樋田知之, 佐藤鮎子, 辻村亨, 河原邦光, 廣島健三, 亀井敏昭, 小田義直:
中皮腫の早期診断に役立つp16FISHとBAP1,MTAP免疫染色.
第58回日本臨床細胞学会総会,
大阪,
2017/05
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22.
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◎廣島健三:
悪性中皮腫の早期病変とは? -その病理学的・細胞学的特徴-.
第58回日本臨床細胞学会総会,
大阪,
2017/05
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23.
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◎涌井清隆, 山本智子, 澤田達男, 柴田亮行, 小林槇雄:
術中迅速細胞診で診断困難であった悪性リンパ腫を合併した髄膜腫の一例.
第58回日本臨床細胞学会総会(春期大会),
大阪,
2017/05
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24.
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◎鍋島 一樹, 木下 義晃, 松本 慎二, 樋田 知之, 佐藤 鮎子, 辻村 亨, 河原 邦光, 廣島 健三, 亀井 敏昭, 小田 義直:
中皮腫の細胞診update.
第106 回日本病理学会総会,
新宿,
2017/04
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25.
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◎廣島健三:
中皮腫の病理診断の最前線.
第106 回日本病理学会総会,
新宿,
2017/04
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26.
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◎中野貴光, 竹内正樹, 廣島健三:
再発後に悪性と判明した小児low grade fibromyxoid sarcomaの治療経験.
第60回日本形成外科学会総会・学術集会,
大阪,
2017/04
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27.
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◎廣島健三:
中皮腫の病理診断.
日中石綿関連癌診断能力向上プロジェクト,
川崎,
2017/09
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