■ Published papers
Original article
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1.
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Tada Y, Hiroshima K, Shimada H, Shingyoji M, Suzuki T, Umezawa H, Sekine I, Takiguchi Y, Tatsumi K, Tagawa M.:
An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol.
Springerplus
5
:195
, 2016.2
DOI:10.1186/s40064-016-1893-2
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2.
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Sciarra A†, Di Tommaso L, Nakano M, Destro A, Torzilli G, Donadon M, Maggioni M, Bosari S, Bulfamante G, Matsuda M, Fujii H, Ichikawa T, Morisaka H, Sano K, Ichikawa S, Roncalli M.:
Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications.
Journal of hepatology
64
(1)
:87-93
, 2016.1
DOI:10.1016/j.jhep.2015.08.031
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3.
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Yamauchi S†, Kawamura K, Okamoto S, Morinaga T, Jiang Y, Shingyoji M, Sekine I, Kubo S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M.:
Replication-competent adenoviruses with the type 35-derived fiber-knob region achieve reactive oxygen species-dependent cytotoxicity and produce greater toxicity than those with the type 5-derived region in pancreatic carcinoma.
Apoptosis : an international journal on programmed cell death
20
(12)
:1587-1598
, 2015.11
DOI:10.1007/s10495-015-1171-8
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4.
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Zhibin Gao†, Kenzo Hiroshima, Xiaodong Wu, Jixian Zhang,Dichu Shao, Huajiang Shao, Hanqing Yang, Toshikazu Yusa, Takako Kiyokawa, Makio Kobayashi, Yasushi Shinohara, Oluf D. Røe,Xing Zhang, Kenji Morinaga:
Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.
American journal of industrial medicine
58
(10)
:1040-1049
, 2015.10
DOI:10.1002/ajim.22494
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5.
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Hida T†, Matsumoto S, Hamasaki M, Kawahara K, Tsujimura T, Hiroshima K, Kamei T, Taguchi K, Iwasaki A, Oda Y, Honda H, Nabeshima K.:
Deletion status of p16 in effusion smear preparation correlates with that of underlying malignant pleural mesothelioma tissue.
Cancer Science
106
(11)
:1635-1641
, 2015.8
DOI:10.1111/cas.12769
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6.
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Takei Y†, Okamoto S, Kawamura K, Jiang Y, Morinaga T, Shingyoji M, Sekine I, Kubo S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M.:
Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells.
Cancer gene therapy
22
(9)
:445-453
, 2015.8
DOI:10.1038/cgt.2015.33.
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7.
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Tada Y†, Hiroshima K, Shimada H, Morishita N, Shirakawa T, Matsumoto K, Shingyoji M, Sekine I, Tatsumi K, Tagawa M.:
A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene.
Springerplus
4
:358
, 2015.7
DOI:10.1186/s40064-015-1123-3
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8.
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Ito T†, Hamasaki M, Matsumoto S, Hiroshima K, Tsujimura T, Kawai T, Shimao Y, Marutsuka K, Moriguchi S, Maruyama R, Miyamoto S, Nabeshima K:
p16/CDKN2A FISH in Differentiation of Diffuse Malignant Peritoneal Mesothelioma From Mesothelial Hyperplasia and Epithelial Ovarian Cancer.
American journal of clinical pathology
143
(6)
:830-838
, 2015.6
DOI:10.1309/AJCPOATJ9L4GCGDA
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9.
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Yang S†, Kawamura K, Okamoto S, Yamauchi S, Shingyoji M, Sekine I, Kobayashi H, Tada Y, Tatsumi K, Hiroshima K, Shimada H, Tagawa M.:
Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression.
BMC cancer
15
:164
, 2015.6
DOI:10.1186/s12885-015-1482-8
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10.
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Kawamura K†, Wada A, Wang JY, Li Q, Ishii A, Tsujimura H, Takagi T, Itami M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M.:
Expression of activation-induced cytidine deaminase is associated with a poor prognosis of diffuse large B cell lymphoma patients treated with CHOP-based chemotherapy.
Journal of Cancer Research and Clinical Oncology
142
(1)
:27-36
, 2015.6
DOI:1007/s00432-015-2001-7
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11.
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Li Q†, Sato A, Shimozato O, Shingyoji M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M:
Administration of DNA encoding the interleukin-27 gene augments anti-tumor responses through non-adaptive immunity.
Scandinavian journal of immunology
82
(4)
:320-327
, 2015.6
DOI:10.1111/sji.12321
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12.
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Walts AE†, Hiroshima K, Marchevsky AM:
Desmoglein 3 and p40 immunoreactivity in neoplastic and nonneoplastic thymus: a potential adjunct to help resolve selected diagnostic and staging problems.
Annals of Diagnostic Pathology
19
(4)
:216-220
, 2015.5
DOI:10.1016/j.anndiagpath
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13.
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Zhong B†, Ma G, Sato A, Shimozato O, Liu H, Li Q, Shingyoji M, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M:
Fas ligand DNA enhances a vaccination effect by coadministered DNA encoding a tumor antigen through augmenting production of antibody against the tumor antigen.
Journal of Immunology Research
(743828)
:1-7
, 2015.5
DOI:10.1155/2015/743828
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14.
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Ma G†, Zhong B, Okamoto S, Jiang Y, Kawamura K, Liu H, Li Q, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M:
A combinatory use of adenoviruses expressing melanoma differentiation-associated gene-7 and replication-competent adenoviruses produces synergistic effects on pancreatic carcinoma cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
36
(10)
:8137-8145
, 2015.5
DOI:10.1007/s13277-015-3555-3
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15.
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Yusa T†, Hiroshima K, Sakai F, Kishimoto T, Ohnishi K, Usami I, Morikawa T, Wu D, Itoi K, Okamoto K, Shinohara Y, Kohyama N, Morinaga K.:
Significant relationship between the extent of pleural plaques and pulmonary asbestos body concentration in lung cancer patients with occupational asbestos exposure.
American journal of industrial medicine
58
(4)
:444-455
, 2015.4
DOI:10.1002/ajim.22430.
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Display 5 items
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Display all(15)
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Review article
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1.
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中野雅行†*:
【混合型肝癌の新病理分類とそれに基づいた画像再評価】 混合型肝癌の病理 胆管細胞癌か肝細胞癌かCK7免疫染色の有用性.
Liver Cancer
21
:5-9
, 2015.11
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2.
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廣島健三†:
増え続ける悪性胸膜中皮腫 ~病理診断の困難さ~.
山形県臨床細胞学会会報
(34)
:2-21
, 2015.10
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3.
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中野雅行†*:
【アルコール医学・医療の最前線2015 Update】 アルコールの基礎医学 アルコール性臓器障害の病理 機能・形態の変化.
医学のあゆみ
254
(10)
:901-905
, 2015.9
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4.
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廣島健三†:
悪性胸膜中皮腫 ~病理診断の困難さ~.
日本職業・災害医学会会誌
63
(4)
:215-218
, 2015.7
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Case report
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1.
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Hida T†, Hamasaki M, Matsumoto S, Abe S, Takakura K, Hiroshima K, Nabeshima K.:
Diffuse intrapulmonary malignant mesothelioma presenting with miliary pulmonary nodules: A case report.
Pathology International
65
(6)
:318-323
, 2015.5
DOI:10.1111/pin.12282.
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Other
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1.
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Hiroshima K†, Wu Di, Hasegawa M, Koh E, Sekine Y, Ozaki D, Yusa T.:
Diagnosis of Malignant Mesothelioma With Effusion Cytology.
Archives of pathology & laboratory medicine
140
:263
, 2016.3
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2.
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Suzuki M†, Mohamed S, Nakajima T, Kubo R, Tian L, Fujiwara T, Suzuki H, Nagato K, Chiyo M, Motohashi S, Yasufuku K, Iyoda A, Yoshida S, Sekine Y, Shibuya K, Hiroshima K, Nakatani Y, Yoshino I, Fujisawa T.:
[Corrigendum] Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis.
International journal of oncology
47
(2)
:791
, 2015.6
DOI:10.3892/ijo.2015.3046
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■ Academic conference presentation
1.
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◎Ann E. Walts, Kenzo Hiroshima, Stephanie McGregor, Aliya Husain, Alberto M. Marchevsky:
BAP1 Immunostain and p16 FISH: Clinical Applicability to Confirm Malignant Mesothelioma in Effusions.
United States & Canadian Academy of Pathology 105th Annual Meeting,
Seattle, Washington,
2016/03
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2.
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◎Kenzo Hiroshima, Di Wu, Mizue Hasegawa, Yasuo Sekine, Daisuke Ozaki, Toshikazu Yusa, Zhibin Gao, Ann E.Walts, Alberto M. Marchevsky, Yuji Tada, Hideaki Shimada, Masatoshi Tagawa:
Utility of BAP1 FISH and immunohistochemistry in Distinguishing between Mesothelioma and Reactive Mesothelial Proliferation. Comparison with Analysis of p16/CDKN2A.
United States & Canadian Academy of Pathology 105th Annual Meeting,
Seattle, Washington,
2016/03
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3.
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◎廣島健三:
悪性中皮腫の病理診断.
浙江省中皮腫診断セミナー,
杭州, 中華人民共和国,
2015/12
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4.
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◎Masatoshi Tagawa, Takao Morinaga, Kiyoko Kawamura, Shinya Okamoto, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tad, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima:
Inhibition of Mdm2 but not Mdm4 binding by small molecules enhances cytotoxic activities of Ad-p53 on mesothelioma.
European Society of Gene and Cell Therapy Annual Meeting,
Helsinki,
2015/09
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5.
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◎Hiroshima K, Wu D, Hasegawa M, Ko E, Sekine Y, Ozaki D, Yusa T:
Diagnosis of malignant mesothelioma with effusion cytology.
2015 Pulmonary Pathology Society Biennial Meeting,
San Francisco,
2015/06
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6.
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◎土岐大介, 高山智裕, 齋藤直, 瀬戸口誠, 廣島健三, 乾政志:
診断に難渋した尿管小細胞癌の1例.
第5回日本泌尿器病理研究会学術集会,
東京,
2016/02
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7.
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◎廣島健三:
石綿(アスベスト)の健康影響や被害について.
平成27年度 石綿(アスベスト)健康診断・治療従事者及び相談業務担当者研修会,
千葉,
2015/12
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8.
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◎廣島健三:
新WHO分類に基づく肺癌および悪性胸膜中皮腫の病理診断の実際 悪性中皮腫の病理診断ー鑑別診断のポイントー.
第56回日本肺癌学会学術集会,
横浜,
2015/11
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9.
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◎廣島健三, 呉迪,長谷川瑞江,黄英哲,関根康雄,尾崎大介,由佐俊和:
BAP1の発現による中皮腫と反応性中皮の鑑別.
第6回JMIG研究会,
北九州,
2015/11
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10.
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◎廣島健三:
体腔液のセルブロックによる中皮腫の診断.
第61回日本病理学会秋期特別総会,
東京,
2015/11
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11.
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◎廣島健三:
悪性中皮腫の病理診断 -鑑別診断のポイント-.
第56回日本肺癌学会学術集会,
横浜,
2015/11
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12.
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◎廣島健三:
胸膜中皮腫のWHO新分類.
第22回石綿・中皮腫研究会,
川崎,
2015/10
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13.
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◎廣島健三, 塩田広宣, 安川朋久, 山川久美, 由佐俊和:
肉腫型中皮腫の診断 -骨形成性中皮腫か骨肉腫か-.
第22回石綿・中皮腫研究会,
川崎,
2015/10
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14.
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◎廣島健三, 呉迪, 長谷川瑞江, 黄英哲, 関根康雄, 尾崎大介, 由佐俊和:
体腔液細胞診だけで中皮腫と確定診断できるか?.
第29回関東臨床細胞学会学術集会,
つくば,
2015/09
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15.
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◎廣島健三:
肺癌のWHO新病理分類.
第13回千葉肺癌カンファレンス,
千葉,
2015/07
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16.
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◎高橋昌樹, 末澤亜紀, 角奈美子, 南部周平, 河合繁夫, 廣島健三, 宮本礼子, 地曳典恵, 寺本穂波, 清水忠夫:
当院の乳腺穿刺吸引細胞診「鑑別困難」症例の検討.
第56回日本臨床細胞学会総会,
松江,
2015/06
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17.
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◎廣島健三:
中皮腫の早期診断における細胞診の役割.
第56回日本臨床細胞学会総会,
松江,
2015/06
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18.
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◎有村健, 関根康雄, 廣島健三, 佐藤昭寿, 畑敦, 柳澤麻子, 長谷川瑞江, 黄英哲, 桂秀樹, 武山廉, 多賀谷悦子, 近藤光子, 玉置淳:
肺癌を疑う末梢肺病変(PPL)に対するEBUS-GS併用、経気管支吸引針生検(TBNA)の検討.
第38回日本呼吸器内視鏡学会学術集会,
東京,
2015/06
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19.
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◎鍋島一樹, 松本慎二, 樋田知之, 濱崎 慎, 亀井敏昭, 廣島健三, 河原邦光, 辻村 亨:
FISH, 細胞診への応用 - 中皮腫を例として.
第104回日本病理学会総会,
名古屋,
2015/05
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20.
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◎廣島健三:
悪性中皮腫の病理診断 - 特に上皮型中皮腫の鑑別診断のポイント.
第104回日本病理学会総会,
名古屋,
2015/04
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21.
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◎有村健, 関根康雄, 廣島健三, 佐藤昭寿, 畑敦, 柳澤麻子, 長谷川瑞江, 黄英哲, 桂秀樹, 武山廉, 多賀谷悦子, 近藤光子, 玉置淳:
末梢肺病変(PPL)に対するEBUS-GS併用TBNAの有効性と安全性の検討.
第55回日本呼吸器学会学術講演会,
東京,
2015/04
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