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 八千代医療センター 病理診断科
Summary Research grants & projects Published papers
Books Academic conference presentation


Professor:

   Hiroshima Kenzou
Assistant Professor:
   Kawamura Shiyunji
■ Summary
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■ Research grants & projects
1.    (Grant No.:*)
 Budget amount:\10,000,000  (Principal investigator)
2.    (Grant No.:*)
 Budget amount:\6,000,000  (Co-investigator)
3.    (Grant No.:21590365)
 Budget amount:\3,500,000  (Co-investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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 1 0 1 0 0 15  0 7 0 1  11 32  4 8  0 2
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■ Published papers
Original article
1. Li Q, Kawamura K, Yamanaka M, Okamoto S, Yang S, Yamauchi S, Fukamachi T, Kobayashi H, Tada Y, Takiguchi Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M:  Upregulated p53 expression activates apoptotic pathways in wild-type p53-bearing mesothelioma and enhances cytotoxicity of cisplatin and pemetrexed.  Cancer gene therapy  19 (3) :218-28 , 2012.3
2. Saitoh M, Niijima M, Takiguchi Y, HIROSHIMA Kenzo, Fujita Y, Nishio K, Tatsumi K:  An early event of EGFR mutation in pleomorphic carcinoma of the lung.  International Journal of Clinical Oncology  16 (6) :770-773 , 2011.12
3. Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shiratori K, Kawamura S, Kobayashi M, Shimizu M, Ban S, Koyama I, Higashi M, Shin N, Ishida K, Morikawa T, Motoi F, Unno M, Kanno A, Satoh K, Shimosegawa T, Orikasa H, Watanabe T, Nishimura K, Harada Y, Furukawa T.:  Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.  The American journal of surgical pathology  35 (12) :1812-7 , 2011.12
4. Tagawa M, Kawamura K, Li Q, Tada Y, HIROSHIMA Kenzo, Shimada H:  A possible anticancer agent, type III interferon, activates cell death pathways and produces antitumor effects.  Clinical & developmental immunology  2011 (479013) :1-6 , 2011.10
5. Nakajima T, Yasufuku K, Suzuki M, HIROSHIMA Kenzo, Nakatani Y, Fujisawa T, Yoshino I:  Thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, orotate phosphoribosyltransferase mRNA expression in lung cancer metastatic lymph node samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration: a pilot study.  Clinical lung cancer  12 (5) :293-297 , 2011.9
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Review article
1. 中野雅行*:  肝細胞癌の診断、治療、予防の最前線 早期肝細胞癌の病理診断 門脈域未浸潤の早期肝細胞癌.  肝臓フォーラム記録集  2011 :46-62 , 2012.3
Case report
1. Suzuki H, Sekine Y, Yamamoto N, Hiroshima K:  Hemilaminectomy for a dumbbell-shaped vertebral hemangioma.  The Thoracic and cardiovascular surgeon  59 (6) :383-384 , 2011.9
2. Ishibashi K, Kishimoto T, Yonemori Y, Hirashiki K, HIROSHIMA Kenzo, Nakatani Y:  Primary hepatoid adenocarcinoma of the uterine corpus: A case report with immunohistochemical study for expression of liver-enriched nuclear factors.  Pathology, research and practice  207 (5) :332-336 , 2011.5
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■ Books
1. 河村俊治:  心筋脂肪化の病理像.  心CT第12号心筋症をMDCTで診る  34-39.  文光堂,  東京、日本, 2012.2
2. 廣島健三:  病理.  新しい診断と治療のABC34/呼吸器5 肺癌  29-37.  最新医学社,  大阪, 2012.1
3. 廣島 健三:  異型腺腫様過形成とは、どのような病変ですか?.  肺癌診療Q&A 一つ上を行く診療の実践  36-38.  中外医学社,  東京, 2011
4. 中谷 行雄, 廣島 健三:  肉腫様癌.  癌診療指針のための病理診断プラクティス 肺癌  158-169.  中山書店,  東京, 2011
5. 廣島 健三, 河村 俊治, 中谷 行雄:  カルチノイド腫瘍.  癌診療指針のための病理診断プラクティス 肺癌  170-179.  中山書店,  東京, 2011
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■ Academic conference presentation
1. ◎Kenzo Hiroshima, Wu Di, Shinji Matsumoto, Kazuki Nabeshima, Toshikazu Yusa, Daisuke Ozaki, Michio Fujino, Yukio Nakatani: The Diagnostic Utility of p16/CDKN2A FISH in Distinction between Sarcomatoid Mesothelioma and Fibrous Pleuritis.  United States and Canadian Academy of Pathology 101st Annual Meeting,  Vancouver, Canada,  2012/03
2. ◎Furuya M, Tanaka R, Koga S, Yatabe Y, Gotoda H, Takagi S, Hsu Y-H, Fujii T, Nagashima Y, Nagahama K, Hiroshima K, Yoshino I, Aoki I, Matsubara O, Oka A, Moritani S, Nakatani Y: Lung Cysts in Birt-Hogg-Dube Syndrome: Unique Histopathological Features and Accelerated m-TOR-Mediated Signaling.  United States and Canadian Academy of Pathology 101st Annual Meeting,  Bancouver, Canada,  2012/03
3. ◎Hamasaki M, Matsumoto S, Nabeshima K, Kamei T, Hiroshima K, Matsuno Y, Kawahara K, Tsujimura T: Morphological Characterization of Pleural Mesothelioma Cells Harboring 9p21 Homozygous Deletion Detected by Fluorescence in Situ Hybridization (FISH) in Effusion Cytology.  United States and Canadian Academy of Pathology 101st Annual Meeting,  Bancouver, Canada,  2012/03
4. ◎廣島健三: 胸膜中皮腫の病理.  石綿曝露と健康障害研究会,  寧波, 中華人民共和国,  2011/11
5. ◎Chen I-pei, Ariizumi Shunichi, Nakano Masayuki, Yamamoto Masakazu: Expression of glypican-3 in well-diferentiated hepatocellular carcinoma.  Asian Pacific HPBA Congress 2011,  Melborne,Australia,  2011/09
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