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 実験動物研究所
Summary Research grants & projects Published papers
Books Academic conference presentation


Assistant Professor：
    Kanai Takao 		Assistant Professor：
    Ueshiba Hidehiro
■ Summary
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■ Research grants & projects
1.    (Grant No.：24108010)
 Budget amount：\1,800,000  (Co-investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. Matheny Christina J, Wei Michael C, Bassik Michael C, Donnelly Alicia J, Kampmann Martin, Iwasaki Masayuki, Piloto Obdulio, Solow-Cordero David E, Bouley Donna M, Rau Rachel, Brown Patrick, McManus Michael T, Weissman Jonathan S, Cleary Michael L：  Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.  Chemistry & biology  20 (11) ：1352-63 , 2013.11   DOI:10.1016/j.chembiol.2013.09.014
2. Kuo Hsu-Ping, Wang Zhong, Lee Dung-Fang, Iwasaki Masayuki, Duque-Afonso Jesus, Wong Stephen H K, Lin Chiou-Hong, Figueroa Maria E, Su Jie, Lemischka Ihor R, Cleary Michael L：  Epigenetic roles of MLL oncoproteins are dependent on NF-κB.  Cancer cell  24 (4) ：423-37 , 2013.10   DOI:10.1016/j.ccr.2013.08.019
3. Ficara Francesca, Crisafulli Laura, Lin Chenwei, Iwasaki Masayuki, Smith Kevin S, Zammataro Luca, Cleary Michael L：  Pbx1 restrains myeloid maturation while preserving lymphoid potential in hematopoietic progenitors.  Journal of cell science  126 (Pt 14) ：3181-91 , 2013.7   DOI:10.1242/jcs.125435
4. Kishimoto Y, Takao KANAI, SATO Kayoko, Lee J, Jeong KS, Shimokado K, Maruyama N, Ishigami A：  Insufficient ascorbic acid intake during gestation induces abnormal cardiac dilation in fetal and neonatal SMP30/GNL knockout mice.  Pediatric Research  73 (5) ：578-584 , 2013.5
5. Akimoto T, Okuhira K, Aizawa K, Wada S, Honda H, Fukubayashi T, Uchida T.：  Skeletal muscle adaptation 1 in response to mechanical stress in p130Cas−/− mice.  Am J Physiol Cell Physiol  304 (6) ：C541-547 , 2013   DOI:doi: 10.1152/ajpcell.00243.2012
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Case report
1. 小川　高，金井　孝夫，山田裕貴，小川ひとみ：  体幹部を中心に広範囲に脱毛のあるダックスですが、痒みが気になります・・・.  小動物臨床  32 (6) ：342-347 , 2013.6
2. 小川　高，金井　孝夫，山田裕貴，小川ひとみ：  胸腺腫大のあったシーズーに突然横断が発症した場合・・・.  小動物臨床  32 (５) ：284-290 , 2013.5
3. 小川　高，金井　孝夫，山田裕貴，小川ひとみ：  線維肉腫に対してはひたすら外科ですが・・・.  小動物臨床  32 (4) ：214-222 , 2013
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■ Books
1. Honda Hiroaki：  Hematopoietic Stem Cell Function and Skeletal Formation: Positive Role of Hemp Gene.  Stem Cells and Cancer Stem Cells, Volume 9, Therapeutic Applications in Disease and Injury Part IV, Hematopoietic Stem Cells  155-162.  Springer,  Berlin, Germany, 2013
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■ Academic conference presentation
1. Hiroaki Honda： Hemp, an epigenetic regulator, sustains hematopoietic stem cell quiescence through regulating FoxO3a and downstream CDK inhibitors.  The 11th Stem Cell Research Conference,  東京,  2013/05
2. ◎樋口智昭, 春田郁子, 柳沢直子, 上芝秀博, 大森深雪, 阿部義廣, 八木淳二： 腸内細菌により誘導される自己免疫性膵炎モデルの膵外病変の検討.  第87回日本細菌学会総会,  東京,  2014/03
3. 本田浩章： 遺伝子改変マウスを用いた放射線感受性と放射線応答機構の解析.  第26回日本動物実験代替法学会,  京都,  2013/12
4. ◎OSAKA Toshifumi, HARUTA Ikuko, MATSUSHITA Noriko, HIGUCHI Tomoaki, YANAGISAWA Naoko, UESHIBA Hidehiro, HASHIMOTO Etsuko, YAGI Junji, TSUNEDA Satoshi： The role of gut microbiota in the progression of non-alcohol fatty liver disease.  Annual meeting of the japanese society for immunology, 2013,  Chiba, Japan,  2013/12
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