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 Department of Biochemistry
Summary Research grants & projects Published papers
Academic conference presentation


Professor:

   Takakuwa Yuuichi
Assistant Professor:
   Koshino Ichirou
   Man'no Sumie
Assistant Professor:
   Arashiki Nobuto
   Saitou Masaki
   Tanaka Shiyoutarou
■ Summary
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■ Research grants & projects
1.    (Grant No.:25460375)
 Budget amount:\2,470,000  (Principal investigator)
2.    (Grant No.:24659485)
 Budget amount:\1,040,000  (Principal investigator)
3.    (Grant No.:25860168)
 Budget amount:\2,600,000  (Principal investigator)
4.    (Grant No.:23770136)
 Budget amount:\1,000,000  (Principal investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. NUNOMURA Wataru*, GASCARD Philippe, WAKUI Hideki, TAKAKUWA Yuichi:  Phosphatidylinositol-4,5 bisphosphate (PIP2) inhibits apo-calmodulin binding to protein 4.1.  Biochemical and biophysical research communications  446 :434-440 , 2014.3   DOI:10.1016/j.bbrc.2014.02.121
2. NUNOMURA Wataru, ISOZUMI Noriyoshi, NAKAMURA Shigeyoshi, JINBO Yuji, OHKI Shinya, KIDOKORO Shun-ichi, WAKUI Hideki, TAKAKUWA Yuichi:  Unique structural changes in calcium-bound calmodulin upon interaction with protein 4.1R FERM domain: novel insights into the calmodulin-dependent regulation of 4.1R FERM domain binding to membrane proteins by calmodulin.  Cell biochemistry and biophysics  :10.1007/s12013-013-9758-6 , 2013.10   DOI:10.1007/s12013-013-9758-6
3. Arashiki Nobuto, Kimata Naoki, Manno Sumie, Mohandas Narla, Takakuwa Yuichi*:  Membrane Peroxidation and Methemoglobin Formation are Both Necessary for Band 3 Clustering: Mechanistic Insights into Human Erythrocyte Senescence.  Biochemistry  52 :5760-5769 , 2013.7
4. Goto Toshihiro, Chiba Ayano, Sukegawa Jun, Yanagisawa Teruyuki, Saito Masaki*, Nakahata Norimichi:  Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G.  Cellular Signaling  25 (3) :690-697 , 2013
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■ Academic conference presentation
1. ◎Saito Masaki: Cholesterol inhibition of phospholipid scrambling in human erythrocyte membranes through its suppression of PLSCR1 activity.  2013 Red cell club meeting,  New York, USA,  2013/10
2. 岡田みどり, 中村裕子, 佐藤 梓, 酒向加菜子, 高桑雄一, 川上順子, 佐藤 紀子, 笠貫宏: 女子中高生の医療系理系進路選択を支援する取り組み「未来の医療を支えるのはあなた」.  日本薬学会第134年会,  熊本、日本,  2014/03
3. ◎TAKAKUWA Yuichi: Senescence mechanism of human erythrocytes.  The 78th annual meeting of the Japanese Society of Hematology,  Sapporo, Japan,  2013/10
4. ◎斎藤将樹, 萬野純恵, 高桑雄一: Phospholipid scramblase 1 (PLSCR1) を介したリン脂質のscrambling機構の検討.  第86回日本生化学会大会,  横浜,  2013/09
5. ◎新敷信人, 高桑雄一: 赤血球‐リポタンパク質間のコレステロール移動のメカニズム.  第86回日本生化学会大会,  横浜、日本,  2013/09
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