Faculty Information

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Department of Physiology, Division of Molecular and Cellular Physiology

Summary	Research grants & projects	Published papers
Academic conference presentation

Professor：

Mitani Shiyouhei

Assistant Professor：
Yoshina Sawako

Assistant Professor：
   HORI Sayaka
   Luna Izuhara
   Suehiro Yuuji
   Dejima Katsufumi
   Yoshida Keita
   Motohashi Tomoko

■ Summary

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■ Research grants & projects

1.	Budget amount：\55,008,360 (Principal investigator)
2.	(Grant No.：16H05123) Budget amount：\2,800,000 (Principal investigator)
3.	(Grant No.：17K18135) Budget amount：\600,000 (Principal investigator)
4.	(Grant No.：16K18517) Budget amount：\500,000 (Principal investigator)
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■ Research works

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Other presentations

Japanese

English

Japanese

English

Domestic

international

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■ Published papers

Original article
1.	Dejima Katsufumi^†, Hori Sayaka^†, Iwata Satoru^†, Suehiro Yuji, Yoshina Sawako, Motohashi Tomoko, Mitani Shohei*： An Aneuploidy-Free and Structurally Defined Balancer Chromosome Toolkit for Caenorhabditis elegans. Cell reports 22 (1) ：232-241 , 2018.1 DOI:10.1016/j.celrep.2017.12.024
2.	Suehiro Yuji^†, Yoshina Sawako, Hori Sayaka, Mitani Shohei： Novel deletion alleles of a C. elegans* gene Y73E7A.1, named as tm6429 and tm6475. Micropublication: biology 10.17912 ：W2808M , 2017.10 DOI:10.17912/W2808M
3.	Hori Sayaka^†, Suehiro Yuji, Yoshina Sawako, Mitani Shohei： Novel deletion alleles of a C. elegans* gene Y48E1C.1, named as tm5468, tm5625 and tm5626. Micropublication: biology 10.17912 ：W2CQ14 , 2017.10 DOI:10.17912/W2CQ14
4.	Yoshina Sawako^†, Hori Sayaka, Suehiro Yuji, Mitani Shohei： Novel deletion alleles of a C. elegans gene C38D4.9, named as tm4476* and tm4561. Micropublication: biology 10.17912 ：W2HH32 , 2017.10 DOI:10.17912/W2HH32
5.	Peng Yu, Zhang Man, Zheng Lingjun, Liang Qian, Li Hanzeng, Chen Jeng-Ting, Guo Hongyan, Yoshina Sawako, Chen Yu-Zen, Zhao Xiang, Wu Xiaoqi, Liu Bin, Mitani Shohei, Yu Jau-Song, Xue Ding： Cysteine protease cathepsin B mediates radiation-induced bystander effects. Nature 547 (7664) ：458-462 , 2017.7 DOI:10.1038/nature23284
6.	Weaver Benjamin P, Weaver Yi M, Mitani Shohei, Han Min： Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Developmental cell 41 (6) ：665-673.e6 , 2017.6 DOI:10.1016/j.devcel.2017.05.013
7.	Yin Jianhua, Huang Yaling, Guo Pengfei, Hu Siqi, Yoshina Sawako, Xuan Nan, Gan Qiwen, Mitani Shohei, Yang Chonglin, Wang Xiaochen： GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans. The Journal of cell biology 216 (6) ：1775-1794 , 2017.6 DOI:10.1083/jcb.201610001
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Review article
1.	Mitani Shohei： Comprehensive functional genomics using Caenorhabditis elegans as a model organism. Proceedings of the Japan Academy. Series B, Physical and biological sciences 93 (8) ：561-577 , 2017.10 DOI:10.2183/pjab.93.036
2.	末廣勇司^†, 榊建二郎, 吉名佐和子, 堀沙耶香, 出嶋克史, 岩田悟, 三谷昌平*：ラットの坐骨神経と下肢骨格筋を用いた容積導体と神経―骨格筋間の信号伝達機構を学ぶ実習. 日本生理学会誌 79 (3) ：44-48 , 2017.8
Case report
1.	IKARI Naoki^†, AOYAMA Shota, SESHIMO Akiyoshi, SUEHIRO Yuji, MOTOHASHI Tomoko, MITANI Shohei, YOSHINA Sawako, TANJI Etsuko, SERIZAWA Akiko, TAMADA Takuji, TANIGUCHI Kiyoaki, YAMAMOTO Masakazu, FURUKAWA Toru*： Somatic mutations and increased lymphangiogenesis observed in a rare case of intramucosal gastric carcinoma with lymph node metastasis. Oncotarget 9 (12) ：10808-10817 , 2018.2 DOI:10.18632/oncotarget.24289
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■ Academic conference presentation

1.	Hori Sayaka, Oda Shigekazu, Suehiro Yuji, Iino Yuichi, Mitani Shohei： OFF-responding Interneurons Control Stimulus Strength-Dependent Sensory Processing. 21th International C.elegans Conference, Los Angeles, USA, 2017/06
2.	SUEHIRO Yuji, MITANI Shohei： The analysis of neurons and molecules required for the response to multiple sensory inputs using two kinds of odorants. he 21st International C. elegans Conference, Los Angeles, CA, USA, 2017/06
3.	◎Katsufumi Dejima, Sayaka Hori, Satoru Iwata, Sawako Yoshina, Yuji Suehiro, Tomoko Motohashi, Shohei Mitani： Balancer chromosome toolkit for C. elegans. 21st International C. elegans Meeting, Los Angeles (USA), 2017/06
4.	吉名佐和子, 三谷昌平： Analysis of Molecular and Cellular Roles of the GON domain in Calcium homeostasis. 第95回日本生理学会大会, 高松, 2018/03
5.	◎碇　直樹,青山翔太,瀬下明良,末廣勇司,本橋智子,三谷昌平,吉名佐和子,丹治悦子,芹澤朗子,山田卓司,谷口清章,山本雅一,古川　徹： Somatic mutations and increased lymphangiogenesis observed in a rare case of intramucosal gastric carcinoma with lymph node metastasis. 第14回日本消化管学会総会学術集会, 東京, 2018/02
6.	SUEHIRO Yuji, MITANI Shohei： Analysis of metabotropic glutamate receptor MGL-1 related to the behavioral choice in Caenorhabditis elegans. The 40th Annual Meeting of the Japan Neuroscience Society, Chiba, JAPAN, 2017/07
7.	◎Hori Sayaka, Oda Shigekazu, Suehiro Yuji, Iino Yuichi, Mitani Shohei： A proneural Atonal defines sensory processing depending on stimulus strength via regulating electrical synapses. Neuroscience2017, Chiba, Japan, 2017/07
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^＊：Corresponding Author
^†：First Author
◎：Presenter