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 Department of Internal Medicine, Division of Rheumatology
Summary Research grants & projects Published papers
Academic conference presentation


Professor:

   Taniguchi Atsuo
   Yamanaka Hisashi
   Kamatani Naoyuki
   Tokuda Hitoshi
   Harigai Masayoshi
Associate Professor:
   Kawaguchi Yasushi
   Ikari Katsunori
   Kotake Shigeru
   Nakajima Ayako
Assistant Professor:
   Ichikawa Naomi
   Katsumata Yasuhiro
   Tateishi Mutsuto
   Tanaka Eiichi
   Tsutsumino Michi
   Nunomura Takako
   Furuya Takefumi
   Yano Kouichirou
Assistant Professor:
   Ichida Hisae
   Tsukahara Sou
   Imamura Hitoshi
   Oosawa Hikota
   Oota Yuuko
   Okamoto Yuuko
   Kataoka Sayuri
   Kawasumi Hidenaga
   Kitahama Mariko
   Kobashigawa Tsuyoshi


   Saitou Asami
   Sakuma Yuu
   Shidara Kumi
   Sugimoto Naoki
   Toki Hiroe
   Tochihara Mari
   TOCHIMOTO Akiko
   Nakayama Masanori
   Nishina Hirokazu
   Hanaoka Masanori


   Higuchi Youko
   Hiroshima Riyou
   Hoshi Daisuke
   Hosozawa Tetsuji
   Mikashima Yoshinori
   Miyawaki Motoko
   Murakoshi Kaoru
   Mochidzuki Takeshi
   Yoshida Shinji
   Sakai Riyouko
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■ Research grants & projects
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. Tanaka Yoshiya, Yamanaka Hisashi, Ishiguro Naoki, Miyasaka Nobuyuki, Kawana Katsuyoshi, Kimura Junko, Agata Naoki, Takeuchi Tsutomu:  Low disease activity for up 3 years after adalimumab discontinuation in patients with early rheumatoid arthritis 2year results of the HOPEFUL 3 study.  Arthritis research & therapy  19 (1) :56 , 2017.3   DOI:10.1186/s13075-017-1264-6
2. Kotak Shigeru, Nanke Yuki, Yago Toru, Kawamoto Manabu, Kobashigawa Tsuyoshi, Yamanaka Hisashi:  Bone Analysis of T-Cell Leukaemia Translocation-Associated Gene (TCTA) Transgenic Mice and Conditional Knockout Mice: Possibility that TCTA Protein Expressed on Osteoclasts Plays a Role as a Novel `Coupling Factor' In Vivo.  Journal of Osteoporosis and Physical Activity  5 (1) :6 , 2017.3
3. Ishiguro Naoki, Atsumi Tatsuya, Harigai Masayoshi, Mimori Tsuneyo, Nishimoto Norihiro, Sumida Takayuki, Takeuchi Tsutomu, Tanaka Yoshiya, Nakasone Ayako, Takagi Nobuhiro, Yamanaka Hisashi:  Effectiveness and safety of tocilizumab in achieving clinical and functional remission, and sustaining efficacy in biologics-naive patients with rheumatoid arthritis: The FIRST Bio study.  Modern rheumatology  27 (2) :217-226 , 2017.3   DOI:10.1080/14397595.2016.1206507
4. Atsumi Tatsuya, Tanaka Yoshiya, Yamamoto Kazuhiko, Takeuchi Tsutomu, Yamanaka Hisashi, Ishiguro Naoki, Eguchi Katsumi, Watanabe Akira, Origasa Hideki, Yasuda Shinsuke, Yamanishi Yuji, Kita Yasuhiko, Matsubara Tsukasa, Iwamoto Masahiro, Shoji Toshiharu, Togo Osamu, Okada Toshiyuki, van der Heijde Désirée, Miyasaka Nobuyuki, Koike Takao:  Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation: 2-year results of the C-OPERA study, a phase III randomised trial.  Annals of the rheumatic diseases  :1 , 2017.2   DOI:10.1136/annrheumdis-2016-210246
5. Miyamae Takako, Takei Syuji, Itoh Yasuhiko, Yamanaka Hisashi:  Survey of attitudes of non-pediatric rheumatologists among councilors of the Japan College of Rheumatology regarding transitional care.  Modern rheumatology  :1-13 , 2017.2   DOI:10.1080/14397595.2017.1285846
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Review article
1. 小橋川 剛, 南家 由紀, 小竹 茂:  【リウマチ性疾患の遺伝要因】 強直性脊椎炎の遺伝要因.  リウマチ科  58 (4) :373-381 , 2017.1
2. 山中寿:  高尿酸血症・痛風の治療ガイドライン.  日本医師会雑誌  145 (7) :1410-1414 , 2016.10
3. 酒井 良子, 針谷 正祥:  RAにおける心血管疾患の発症リスク.  リウマチ科  56 (1) :117-124 , 2016.7
4. 八子 徹, 南家 由紀, 川本 学, 小竹 茂:  TNFαの骨代謝に対する役割 骨破壊か、骨形成か?.  リウマチ科  55 (6) :623-632 , 2016.6
5. Kotake Shigeru, Nanke Yuki:  Mouse Osteoblasts Play a Crucial Role in the Immune System.  The American journal of pathology  186 (5) :1078-80 , 2016.5   DOI:10.1016/j.ajpath.2016.01.009
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Case report
1. Nanke Yuki, Kobashigawa Tsuyoshi, Yamanaka Hisashi, Kotake Shigeru*:  A case of entheropathic arthritis successfully treated with methotrexate.  Japanese Journal of Clinical Immunology  39 (3) :219-222 , 2016   DOI:10.2177/jsci.39.219
Other
1. 勝又 康弘:  【全身性エリテマトーデスの病態解明・治療法の進歩】SLEに対するシクロスポリン・タクロリムス.  リウマチ科  57 (3) :282-291 , 2017.3
2. 酒井 良子, 針谷 正祥:  関節リウマチにおける歯周病感染、喫煙などの環境要因と遺伝要因との相互作用.  リウマチ科  57 (1) :84-89 , 2017.1
3. 猪狩勝則:  ゲノム解析からRA病態におけるシトルリン化の意義を探る.  分子リウマチ治療  9 (4) :165-167 , 2016.10
4. 酒井 良子, 針谷 正祥:  【高齢者におけるリウマチ性疾患と膠原病】 リウマチ・膠原病疾患の感染症リスクに関する疫学データ.  Geriatric Medicine  54 (9) :883-886 , 2016.9
5. 堤野 みち, 山中 寿:  【膠原病と腎障害】 関節リウマチに対する生物学的製剤.  腎と透析  81 (3) :401-408 , 2016.9
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■ Books
1. 矢野紘一郎:    リウマチ足の診かた,考え方  1.  中外医学社,  東京, 2017.3
2. 猪狩勝則:  外科.  今日の治療指針 2017年版  1099-1100.  医学書院,  日本, 2017.1
3. 中島 亜矢子:  【高尿酸血症・低尿酸血症-最近の診断と治療-】 高尿酸血症の臨床 高尿酸血症・痛風の検査・診断・治療 治療 薬物治療 痛風発作治療薬.  日本臨床  221-224.  (株)日本臨床社,  東京, 2016.11
4. 山中寿:  関節リウマチ.  痛い!首腰ひざのいい病院2017  74-77.  週間朝日MOOK,  東京, 2016.10
5. 山中寿:  高尿酸血症.  今日の整形外科 治療指針  159-160.  医学書院,  東京, 2016.5
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■ Academic conference presentation
1. ◎Hirahara Shinya, Katsumata Yasuhiro, Kawaguchi Yasushi, Yamanaka Hisashi: Usefulness of soluble PD-1 in patients with systemic lupus erythematosus.  LUPUS,  Melbourne, Australia,  2017/03
2. Ken-ei Sada, Masayoshi Harigai, Joichi Usui, Kunihiro Yamagata, Sakae Homma, Hiroaki Dobashi, Naotake Tsuboi, Akihiro Ishizu, Hitoshi Sugiyama, Yasunori Okada, Yoshihiro Arimura, Seiichi Matsuo, Hirofumi Makino: Treatment response among severities in Japanese patients with microscopic polyangiitis.  18th Vasculitis and ANCA Workshop,  Tokyo.Japan,  2017/03
3. Masayoshi Harigai, Yoshihiro Arimura, Michi Tanaka: A clinical trial of tocilizumab for microscopic polyangiitis and granulomatosis with polyangiitis.  18th Vasculitis and ANCA Workshop,  Tokyo.Japan,  2017/03
4. Michi Tanaka, Ken-ei Sada, Yoshihiro Arimura, Seiichi Matsuo, Hirofumi Makino, Masayoshi Harigai: Inflammatory cytokine profiles in patients with anti-neutrophilic cytoplasmic antibody-associated vasculitis.  18th Vasculitis and ANCA Workshop,  Tokyo.Japan,  2017/03
5. ◎Yuka Iwahashi, Aya Kawasaki, Fumio Hirano, Ken-ei Sada, Shigeto Kobayashi, Hidehiro Yamada, Hiroshi Furukawa, Kunihiro Yamagata, Takayuki Sumida, Nobuyuki Miyasaka, Shigeto Tohma, Shoichi Ozaki, Seiichi Matsuo, Hiroshi Hashimoto, Hirofumi Makino, Yoshihiro Arimura, Masayoshi Harigai , Naoyuki Tsuchiya: Association of TNFSF4 Polymorphism with Proteinase 3 ANCA Positive Vasculitis in a Japanese Population.  18th Vasculitis and ANCA Workshop,  Tokyo.Japan,  2017/03
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