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 Department of Internal Medicine, Division of Rheumatology
Summary Research grants & projects Published papers


Associate Professor:
   KAWAGUCHI Yasushi
   IKARI Katsunori
Assistant Professor:
   TANAKA Eiichi
   NANKE Yuki
   FURUYA Takefumi
Assistant Professor:
   ICHIKAWA Naomi
   TAKAGI Kae
   ICHIDA Hisae
   KATSUMATA Yasuhiro
   GONO Takahisa
   SUGIMOTO Naoki
   TOCHIMOTO Akiko
   MASUDA Ikuko
   MOCHIDZUKI Takeshi
   YANO Kouichirou
■ Summary
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■ Research grants & projects
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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 3 0 48 9 2 12  0 6 0 1  3 24  2 17  0 27
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■ Published papers
Original article
1. Sato Eri, Yamanaka Hisashi:  JESMR study.  Frontiers in Rheumatology & Clinical Immunology  6 (1) :26-29 , 2012.2
2. Takagi Kae, Kaguchi yasushi, Ota Yuko:  Notch pathway is activated in SSc.  Rheumatology  51 (supplement2) :30 , 2012.2
3. Furukawa Toru, Kuboki Yuko, Tanji Etsuko, Yoshida Shoko, Hatori Takashi, Yamamoto Masakazu, Shibata Noriyuki, Shimizu Kyoko, Kamatani Naoyuki, Shiratori Keiko*:  Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas.  Scientific reports of the Istituto superiore di sanità  1 :161 , 2011.11   DOI:10.1038/srep00161
4. MOMOHARA Shigeki, KAWAKAMI Kousei, IWAMOTO Takuji, YANO Koichiro, SAKUMA Yu, HIROSHIMA Ryo, IMAMURA Hitoshi, MASUDA Ikuko, TOKITA Asami, IKARI Katsunori:  Prosthetic joint infection after total hip or knee arthroplasty in rheumatoid arthritis patients treated with nonbiologic and biologic disease-modifying antirheumatic drugs.  Modern rheumatology  21 (5) :469-475 , 2011.10   DOI:10.1007/s10165-011-0423-x
5. MOMOHARA Shigeki, INOUE Eisuke, IKARI Katsunori, YANO Koichiro, TOKITA Asami, SUZUKI Taku, SAKUMA Yu, HIROSHIMA Ryo, KAWAKAMI Kosei, MASUDA IKuko, IWAMOTO Takuji, TANIGUCHI Atsuo, YAMANAKA Hisashi:  Efficacy of total joint arthroplasty in patients with established rheumatoid arthritis: improved longitudinal effects on disease activity but not on health-related quality of life.  Modern rheumatology  21 (5) :476-481 , 2011.10   DOI:10.1007/s10165-011-0432-9
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Review article
1. tanaka eiichi,Mannalithara A, Inoue E, Iikuni N, Taniguchi A, Momohara S, Singh G, Yamanaka H:  Effects of long-term corticosteroid usage on functional disability in patients with early rheumatoid arthritis, regardless of controlled disease activity.  Rheumatol Int.  32 (3) :749-57 , 2012.3
2. tanaka eiichi, taniguchi atsuo, momohara shigeki, yamanaka hisashi:  Effects of long-term corticosteroid usage on functional disability in patients with early rheumatoid arthritis, regardless of controlled disease activity.  Rheumatology international  32 (3) :749-57 , 2012.3
3. Kotake Shigeru, Yago Toru, Kawamoto Manabu, Nanke Yuki:  Role of osteoclasts and interleukin-17 in the pathogenesis of rheumatoid arthritis: crucial 'human osteoclastology'.  Journal of Bone and Mineral Metabolism  30 (2) :125-135 , 2012.3   DOI:10.1007/s00774-011-0321-5
4. 齋藤 和義, 針谷 正祥, 川上 純:  RAの関節破壊をどうコントロールするか.  Frontiers in Rheumatology & Clinical Immunology  6 (1) :9月20日 , 2012.2
5. Kotake Shigeru, Nanke Yuki:  Spinal tophaceous gout.  Internal Medicine  51 (3) :237-278 , 2012.2   DOI:10.2169/internalmedicine.51.6724
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Case report
1. 南家 由紀, 小橋川 剛, 八子 徹, 山中 寿, 小竹 茂:  三叉神経障害、外転神経麻痺をきたしたシェーグレン症候群疑い、関節リウマチ、不全型ベーチェット病の一例.  日本臨床免疫学会会誌  35 (5) :429-432 , 2012.1
2. NANKE Yuki*, ISHIGURO Naoko, YAGO Toru, KOBASHIGAWA Tsuyoshi, KAWAKAMI Michiko, KAWASHIMA Makoto, KOTAKE Shigeru:  A case of Weber-Christian disease with later development of rheumatoid arthritis.  Japanese Journal of Clinical Immunology  34 (1) :49-52 , 2011   DOI:10.2177/jsci.34.49
Other
1. 西本 和正, 猪狩 勝則, 桃原 茂樹:  RA疾患感受性とエンドムチン.  リウマチ科  47 (3) :277-283 , 2012.3
2. 渡部 香織, 針谷 正祥:  寛解基準に用いる患者VASの正しい尋ね方を教えてください.  Frontiers in Rheumatology & Clinical Immunology  6 (1) :46 , 2012.2
3. 田中 みち, 針谷 正祥:  【心血管疾患と炎症】 治す 血管炎症候群と新しい免疫抑制薬.  Heart View  16 (2) :184-191 , 2012.2
4. 針谷 正祥:  【最新の膠原病診療-そのパラダイムシフト】 膠原病総論.  日本医師会雑誌  140 (11) :2291-2294 , 2012.2
5. 山崎 隼人, 針谷 正祥:  【生物学的製剤時代の関節リウマチ最新治療戦略-5剤の使い方と新規治療薬の可能性-】 エタネルセプトは週1回投与が可能.  Mebio  29 (1) :47-53 , 2012.1
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■ Books
1. KawaguchiYasushi, TakagiKae:  厚生労働科学研究費補助金、難治性疾患克服研究事業、混合性結合組織病の病態解明、早期診断と治療法の確立に関する研究;平成23年度 総括・分担研究報告書;MCTD,SLE、SScにおけるNOS2遺伝子多型とPAHとの関連.  厚生労働科学研究費補助金、難治性疾患克服研究事業、混合性結合組織病の病態解明、早期診断と治療法の確立に関する研究;平成23年度 総括・分担研究報告書  4-8.  厚生省,  東京、日本, 2012.3
2. ◎山中寿:  徹底管理!痛風・高尿酸血症の対策.  NHKきょうの健康Xここが聞きたい! 名医にQ お医者さん名鑑  195.  主婦と生活社,  東京, 2012.3
3. 渡部 香織, 針谷 正祥:  寛解基準に用いる患者VASの正しい尋ね方を教えてください.  Frontiers in Rheumatology & Clinical Immunology  46.  (株)メディカルレビュー社,  日本, 2012.2
4. ◎谷口敦夫, 山中寿:  尿酸代謝総論.  内分泌・糖尿病内科学  58-60.  シュプリンガー・ジャパン株式会社,  東京, 2011.9
5. ◎山中寿, 山本徹也:  高尿酸血症・痛風の現状と最新の治療戦略.  Progress in Medicine  75-80.  株式会社ライフ・サイエンス,  東京, 2011.4
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■ Academic conference presentation
1. ◎Takagi kae, kawaguchi Yasushi, Ota Yuko, Okamoto Akiko, Fukasawa Chikako, Yamanaka Hisashi: Notch pathway is activated in Systemic Sclerosis (SSc).  2nd Systemic Sclerosis World Congress,  Madrid, Spain,  2012/02
2. Harigai M.: T2T case study -Best case sharing.  Korea-Japan T2T joint meeting.,  Seoul, Republic of Korea.,  2012/02
3. *Yamanaka Hisashi: Emerging evidence in Asia on the immunogenicity of biologics and their clinical implications.  The 5th Asian Congress on Autoimmunity,  Singapore, Singapore,  2011/11
4. *Yamanaka Hisashi: New treatment target in patients with RA - Where are we and where are we going?.  The 5th Asian Congress on Autoimmunity,  Singapore, Singapore,  2011/11
5. *Yamanaka Hisashi, Harigai Masayoshi, Inokuma Shigeko, Ishiguro Naoki, Ryu Junnosuke, Takei Syuji, Takeuchi Tsutomu, Tanaka Yoshiya, Sano Youko, Koike Takao: Postmarketing Surveillance of Tocilizumab for Rheumatoid Arthritis In Japan-Full Analysis Report of 7,901 Patients.  2011The ACR/ARHP Annual Scientific Meeting,  Chicago, USA,  2011/11
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