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 八千代医療センター 病理診断科
Summary Research grants & projects Published papers
Books Academic conference presentation


Professor:

   HIROSHIMA Kenzo
Associate Professor:
   増永 敦子
Assistant Professor:
   Oide Takashi
■ Summary
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■ Research grants & projects
1.  
 Budget amount:\4,320,000  (Principal investigator)
2.  
 Budget amount:\1,950,000  (Co-investigator)
3.  
 Budget amount:\4,320,000  (Co-investigator)
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■ Research works
Journal Book Presentation Other presentations
JapaneseEnglish JapaneseEnglish Domesticinternational
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■ Published papers
Original article
1. Nicholson AG, Torkko K, Viola P, Duhig E, Geisinger K, Borczuk AC, Hiroshima K, Tsao MS, Warth A, Lantuejoul S, Russell PA, Thunnissen E, Marchevsky A, Mino-Kenudson M, Beasley MB, Botling J, Dacic S, Yatabe Y, Noguchi M, Travis WD, Kerr K, Hirsch FR, Chirieac LR, Wistuba II, Moreira A, Chung JH, Chou TY, Bubendorf L, Chen G, Pelosi G, Poleri C, Detterbeck FC, Franklin WA.:  Interobserver Variation Among Pathologists And Refinement Of Criteria In Distinguishing Separate Primary Tumours From Intrapulmonary Metastases In Lung.  Journal of Thoracic Oncology  13 (2) :205-217 , 2018.2   DOI:10.1016/j.jtho.2017.10.019.
2. Rosen LE, Karrison T, Ananthanarayanan V, Gallan AJ, Adusumilli PS, Alchami FS, Attanoos R, Brcic L, Butnor KJ, Galateau-Sallé F, Hiroshima K, Kadota K, Klampatsa A, Stang NL, Lindenmann J, Litzky LA, Marchevsky A, Medeiros F, Montero MA, Moore DA, Nabeshima K, Pavlisko EN, Roggli VL, Sauter JL, Sharma A, Sheaff M, Travis WD, Vigneswaran WT, Vrugt B, Walts AE, Tjota MY, Krausz T, Husain AN.:  Nuclear grade and necrosis predict prognosis in malignant epithelioid pleural mesothelioma: a multi-institutional study.  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc  31 (4) :598-606 , 2018.1   DOI:10.1038/modpathol.2017.170.
3. Arimura K, Sekine Y, Hiroshima K, Sato A, Hasegawa M, Katsura H, Tagaya E, Kondo M, Tamaoki J:  The efficacy of transbronchial needle aspiration with endobronchial ultrasonography using a guide sheath for peripheral pulmonary lesions suspected to be lung cancer.  Respiratory investigation  55 (6) :365-371 , 2017.11   DOI:10.1016/j.resinv.2017.08.004.
4. Morinaga T, Nguyen TTT, Zhong B, Hanazono M, Shingyoji M, Sekine I, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Tagawa M.:  An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced.  Virology journal  14 (1) :219 , 2017.11   DOI:10.1186/s12985-017-0888-0
5. Kinoshita Y, Hida T, Hamasaki M, Matsumoto S, Sato A, Tsujimura T, Kawahara K, Hiroshima K, Oda Y, Nabeshima K.:  A combination of MTAP and BAP1 immunohistochemistry in pleural effusion cytology for the diagnosis of mesothelioma.  Cancer  126 (1) :54-63 , 2017.10   DOI:10.1002/cncy.21928
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Review article
1. 廣島健三*:  中皮腫診断の新たな局面.  肺癌  57 (4) :259-271 , 2017.8
2. Kenzo Hiroshima*, Mari Mino-Kenudson:  Update on large cell neuroendocrine carcinoma.  Translational Lung Cancer Research  6 (5) :530-539 , 2017.6   DOI:10.21037/tlcr.2017.06.12 Link
3. 中野雅行*, 谷一郎:  細胆管細胞癌再考 -コンセプト癌ー.  肝胆膵  74 (5) :717-723 , 2017.5
4. 廣島健三, 多田裕司:  悪性中皮腫UPDATE はじめに.  医学のあゆみ  261 (2) :127 , 2017.4
5. 廣島健三:  悪性中皮腫UPDATE 中皮腫の病理診断のupdate.  医学のあゆみ  261 (2) :150-156 , 2017.4
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Case report
1. Masunaga A, Ishibashi F, Koh E, Oide T, Sekine Y, Hiroshima K:  Possible relationship between fibrosis of IgG4-related thymitis and the profibrotic cytokines, transforming growth factor beta 1, interleukin 1 beta and interferon gamma: a case report.  Diagnostic Pathology  13 (1) :6 , 2018.1   DOI:10.1186/s13000-018-0684-1 Link
2. Kimura N, Hasegawa M, Hiroshima K.:  SMARCB1/INI1/BAF47- deficient pleural malignant mesothelioma with rhabdoid features.  Pathology International  68 (2) :128-132 , 2018.1   DOI:10.1111/pin.12623
3. Oide T*, Mitsuishi T:  Pigmented Macule - A Skin Manifestation of Invasive Breast Cancer.  The New England journal of medicine  377 :1777 , 2017.11   DOI:10.1056/NEJMicm1704791 Link
4. Oide T*, Hiroshima K, Shibuya K, Nakatani Y.:  Primary Pulmonary Meningioma Presenting as a Coin Lesion.  Internal Medicine  56 :2073-2074 , 2017.8   DOI:10.2169/internalmedicine.56.8481. Link
5. Hasegawa M, Sakai F, Okabayashi A, Sato A, Yokohori N, Katsura H, Asano C, Kamata T, Koh E, Sekine Y, Hiroshima K, Ogura T, Takemura T.:  Intravenous Immunoglobulin Monotherapy for Granulomatous Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency.  Internal Medicine  56 (21) :2899-2902 , 2017.7   DOI:10.2169/internalmedicine.7757-16 Link
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Other
1. 佐藤之俊, 廣島健三, 木浦勝行, 薄田勝男, 大林千穂, 河原邦光, 桜田晃, 羽場礼次, 三浦弘之, 三窪将史, 吉澤明彦, 柿沼廣邦, 竹中明美, 三宅真司:  悪性胸膜中皮腫細胞診断の手引き.  日本肺癌学会  https ://www.haigan.gr.jp/uploads/files/photos/1539.pdf , 2017.12 Link
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■ Books
1. 廣島健三:  細胞診断.  呼吸器疾患 診断治療アプローチ 第3巻 「肺癌」  66-69.  中山書店,  東京, 2018.2
2. 廣島健三:  微少浸潤性腺癌とは,どのような病変ですか?.  肺癌診療Q&A(第3版)  12-16.  中外医学社,  東京, 2017.9
3. 廣島健三:  異型腺腫様過形成とは,どのような病変ですか?.  肺癌診療Q&A(第3版)  8-11.  中外医学社,  東京, 2017.9
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■ Academic conference presentation
1. ◎Kenzo Hiroshima, Di Wu, Yasuo Sekine, Daisuke Ozaki, Toshikazu Yusa, Shoutaro Tsuji, Yohei Miyagi, Aliya Husain, Kohzoh Imai: HEG1 is a Novel Mucin-like Membrane Protein That is Useful for the Diagnosis of Malignant Mesothelioma.  USCAP 2018 Annual Meeting,  Vancouver, Canada,  2018/03
2. ◎Toshiaki Kawai, Koji Kameda, Hiroshi Nakashima, Kenzo Hiroshima: Reduced expression of SMARCB1/INI1 protein in malignant mesothelioma.  USCAP 2018 Annual Meeting,  Vancouver, Canada,  2018/03
3. ◎Kenzo Hiroshima: Scientific Highlights - Biology/Pathology and Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies.  IASLC 18th World Conference on Lung Cancer,  Yokohama,  2017/10
4. ◎Kenzo Hiroshima, Di Wu, Toshikazu Yusa, Daisuke Ozaki, Eitetsu Koh, Yasuo Sekine, Reiji Haba, Kota
Washimi, Kazuki Nabeshima, Tohru Tsujimura: FISH Analysis of p16 and BAP1 Immunohistochemistry for the Diagnosis of Mesothelioma.  IASLC 18th World Conference on Lung Cancer,  Yokohama,  2017/10
5. ◎Kenzo Hiroshima, Di Wu, Zhibin Gao, Kazuki Nabeshima , Tohru Tsujimura: Analysis of p16 deletion and loss of BAP1 in peritoneal mesotheliomas in Japan and in China.  Pulmonary Pathology Society 2017 Meeting,  Chicago, U.S.A.,  2017/06
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