MARUYAMA Takashi    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position
言語種別	日本語
発表タイトル	Development of Autofocus Surgical Microscope for Neurosurgery with Fluorescence Spectra Measurement
学会区分	全国規模の学会
発表形式	口頭
発表年月日	2008/10/31
学会抄録	日本コンピュータ外科学会誌 10(3),297-298 2008
概要	Abstract: It is important to remove tumor accurately in neurosurgery, such as the resection of malignant glioma. However, gross total removal is difficult for glioma extending eloquent area to preserve important brain function. 5-Aminolevulinic Acid (5-ALA) accumulates on tumors and metabolizes to ProtoporphyrinlX (PpIX), which is a fluorescent substance. Intra-operative detection of 5-ALA-induced PpIX fluorescence provides useful information for tumor detection. In this study, we developed an automatically focusing surgical microscope system with a guide laser measurement. The system is connected with a fluorescence spectra measurement device, which can detect the fluorescence in tumor detection. We performed a set of experiments for evaluation of the autofocus device and measurement of the fluorescence spectra. Experimental Results showed that the accuracy of autofocus largely depends on the scattering of the guide laser and the condition of the brain surface. Our future works include the improvement of the accuracy of autofocus device and installation of tumor evaporation ablation laser to the microscope system.