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カナイ タカユキ
金井 貴幸 所属 医学部 医学科（東京女子医科大学病院） 職種 講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Evaluation of four-dimensional computed tomography (4D-CT)-based pulmonary ventilation: The high correlation between 4D-CT ventilation and (81m)Kr-planar images was found. |
| 掲載誌名 | 正式名：Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 略 称：Radiother Oncol ISSNコード：18790887/01678140 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 119(3),pp.444-8 |
| 著者・共著者 | Kanai Takayuki, Kadoya Noriyuki, Ito Kengo, Kishi Kazuma, Dobashi Suguru, Yamamoto Takaya, Umezawa Rei, Matsushita Haruo, Takeda Ken, Jingu Keiichi |
| 担当区分 | 筆頭著者 |
| 発行年月 | 2016/06 |
| 概要 | PURPOSE:To evaluate four-dimensional computed tomography (4D-CT)-derived pulmonary ventilation by comparing with (81m)Kr-gas ventilation (VRI). We also proposed two methods to improve the functional accuracy of 4D-CT ventilation images and evaluated these methods.METHODS AND MATERIALS:Eleven lung cancer patients with 4D-CT and VRI were analyzed. Hounsfield unit-based (VHU) and a Jacobian-based (VJac) 4D-CT ventilation images were calculated. They were evaluated by voxel-by-voxel spearman's rank correlation coefficient (r) between 4D-CT ventilation and VRI images. After applying an averaging ventilation method and a slope calculating method, correlations were also calculated.RESULTS:4D-CT ventilation showed the high correlation to VRI (r=0.875 with VHU). An averaging method brought significantly higher (p=0.012) correlations to nuclear medicine images with VHU. The improvement was not significant (p=0.619) with VJac. Slope calculating method improved the correlation with VHU and slightly worsened the correlation with VJac.CONCLUSIONS:The averaging method we proposed might be useful to improve 4D-CT ventilation images. We found good agreement between 4D-CT ventilation and nuclear medicine ventilation, indicating the high physiologic accuracy of 4D-CT ventilation. |
| DOI | 10.1016/j.radonc.2016.04.030 |
| PMID | 27165614 |