ニツタ コウサク   Nitta Kosaku
  新田 孝作
   所属   その他 その他
   職種   非常勤嘱託
論文種別 総説
言語種別 英語
査読の有無 査読あり
表題 Cell sheet-based tissue engineering for mesothelial cell injury.
掲載誌名 正式名:Contributions to nephrology
略  称:Contrib Nephrol
ISSNコード:1662-2782(Electronic)0302-5144(Linking)
掲載区分国外
巻・号・頁 185,pp.66-75
著者・共著者 Kawanishi Kunio†, Nitta Kosaku
担当区分 最終著者
発行年月 2015/07
概要 Mesothelial cells are an integral part of the peritoneum and play an important role in maintaining its structure and functions. A number of studies have been performed to evaluate the ability of mesothelial cells to regenerate and transdifferentiate. Mesothelial cells are also involved in repairing the damage to the peritoneum as a result of surgery or peritonitis. Previous cell sheet engineering research has made it possible to transplant cells that retain their function, and stacking different types of cells in cell sheet layers has also become possible. Mesothelial cell transplantation as a means of achieving peritoneal regeneration needs to be performed under conditions in which the surface area of the visceral peritoneum is large and the area of mesothelial cell damage is small. In this chapter, we explain cell sheet engineering as a technology for transplanting cells in which a variety of intercellular adhesion and cell membrane molecules remain intact and the application of this technology to peritoneal regeneration.
DOI 10.1159/000380971
文献番号 26023016