SHIMIZU Kyoko
   Department   Other, Other
   Position  
Article types Review article
Language English
Peer review Non peer reviewed
Title Evidence-based clinical practice guidelines for chronic pancreatitis 2021.
Journal Formal name：Journal of gastroenterology
Abbreviation：J Gastroenterol
ISSN code：14355922/09441174
Domestic / ForeginDomestic
Volume, Issue, Page 57(10),pp.709-724
Author and coauthor SHIMIZU Kyoko†, ITO Tetsuhide, IRISAWA Atsushi, OHTSUKA Takao, OHARA Hirotaka, KANNO Atsushi, KIDA Mitsuhiro, SAKAGAMI Junichi, SATA Naohiro, TAKEYAMA Yoshifumi, TAHARA Junko, HIROTA Morihisa, FUJIMORI Nao, MASAMUNE Atsushi, MOCHIDA Satoshi, ENOMOTO Nobuyuki, SHIMOSEGAWA Tooru, KOIKE Kazuhiko
Authorship Lead author
Publication date 2022/10
Summary BACKGROUND:Chronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress.METHODS:The clinical practice guidelines for CP in Japan were revised in 2021 based on the 2019 Japanese clinical diagnostic criteria for CP, which incorporate the concept of a pathogenic fibro-inflammatory syndrome in the pancreas. In this third edition, clinical questions are reclassified into clinical questions, background questions, and future research questions.RESULTS:Based on analysis of newly accumulated evidence, the strength of evidence and recommendations for each clinical question is described in terms of treatment selection, lifestyle guidance, pain control, treatment of exocrine and endocrine insufficiency, and treatment of complications. A flowchart outlining indications, treatment selection, and policies for cases in which treatment is ineffective is provided. For pain control, pharmacological treatment and the indications and timing for endoscopic and surgical treatment have been updated in the revised edition.CONCLUSIONS:These updated guidelines provide clinicians with useful information to assist in the diagnosis and treatment of CP.
DOI 10.1007/s00535-022-01911-6
PMID 35994093