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ヤマグチ シゲキ
YAMAGUCHI SHIGEKI
山口 茂樹 所属 医学部 医学科（東京女子医科大学病院） 職種 教授・基幹分野長 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Verification of oncological local control for hand-assisted laparoscopic abdominal lymph node dissection in esophageal cancer surgery: a propensity score-matched analysis. |
| 掲載誌名 | 正式名：Esophagus 略 称：Esophagus ISSNコード：16129067/16129059 |
| 掲載区分 | 国内 |
| 巻・号・頁 | 18(2),pp.187-194 |
| 著者・共著者 | Miyawaki Yutaka, Sato Hiroshi, Fujiwara Naoto, Aoyama Junya, Oya Shuichiro, Sugita Hirofumi, Hirano Yasumitsu, Sakuramoto Shinichi, Okamoto Kojun, Yamaguchi Shigeki, Koyama Isamu |
| 発行年月 | 2021/04 |
| 概要 | BACKGROUND:In esophageal cancer, long-term outcomes of minimally invasive surgery using endoscopic surgery are currently being verified. However, most trials have compared thoracic procedures; few studies have focused on the abdominal procedures, which are important for lymph node dissection in radical esophageal cancer surgery. Hand-assisted laparoscopic surgery (HALS) is a simple and minimally invasive procedure. Although HALS superiority in short-term outcomes has been reported, its oncological safety in esophageal cancer remains unclear. Therefore, we retrospectively evaluated oncological safety of HALS compared with that of conventional open laparotomy (OL) in radical surgery for thoracic and abdominal esophageal cancer.METHODS:We retrospectively analyzed the postoperative survival in 142 patients who underwent radical esophageal cancer surgery at our hospital between May 2012 and May 2017, with and without propensity score matching (PSM) between groups.RESULTS:Before PSM, OL (n = 65) and HALS (n = 77) groups differed significantly in overall survival (OS) (3-year OS rate: 74.2% and 87.3%, respectively; log-rank p = 0.040). Additionally, clinical abdominal lymph node metastasis (cALNM) independently predicted OS (p = 0.031). After PSM, the OL and HALS groups did not differ significantly in OS (3-year OS rate: 80.5% and 89.8%, respectively; log-rank p = 0.716). There was no statistically significant difference in abdominal-specific recurrence-free survival between the OL and HALS group before and after PSM.CONCLUSION:HALS may be a well-accepted procedure for radical esophagectomy in esophageal cancer, with oncological safety, including local control specific to the abdomen, comparable to that of the conventional OL. |
| DOI | 10.1007/s10388-020-00763-4 |
| PMID | 32734587 |