MURAGAKI Yoshihiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Visiting Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Correlation between fractional anisotropy changes in the targeted ventral intermediate nucleus and clinical outcome after transcranial MR-guided focused ultrasound thalamotomy for essential tremor: results of a pilot study
Journal Formal name:Journal of neurosurgery
Abbreviation:J Neurosurg
ISSN code:00223085/19330693
Domestic / ForeginForegin
Volume, Issue, Page 132(2),pp.568-573
Author and coauthor HORI Hiroki†, YAMAGUCHI Toshio, KONISHI Yoshiyuki, TAIRA Takaomi, MURAGAKI Yoshihiro*
Authorship Last author,Corresponding author
Publication date 2019/02
Summary CLINICAL ARTICLE
OBJECTIVE This study evaluated changes of fractional anisotropy (FA) in the ventral intermediate nucleus (VIM) of the
thalamus after transcranial MR-guided focused ultrasound (TcMRgFUS) thalamotomy and their associations with clinical
outcome.
METHODS Clinical and radiological data of 12 patients with medically refractory essential tremor (mean age 76.5 years)
who underwent TcMRgFUS thalamotomy with VIM targeting were analyzed retrospectively. The Clinical Rating Scale for
Tremor (CRST) score was calculated before and at 1 year after treatment. Measurements of the relative FA (rFA) values,
defined as ratio of the FA value in the targeted VIM to the FA value in the contralateral VIM, were performed before
thalamotomy, and 1 day and 1 year thereafter.
DOI 10.3171/2018.10.JNS18993
PMID 30771772