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MURAGAKI Yoshihiro
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Visiting Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma |
| Journal | Formal name：Journal of Neurosurgery Abbreviation：J Neurosurg ISSN code：19330693 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 115(2),pp.248-255 |
| Author and coauthor | MURAGAKI Yoshihiro†, MARUYAMA Takashi, ISEKI Hiroshi, TANAKA Masahiko, SHINOHARA Chie, TAKAKURA Kintomo, TSUBOI Koji,YAMAMOTO Tetsuya, MATSUMURA Akira, MATSUTANI Masao, KARASAWA Katsuyuki,SHIMADA Katsunori, YAMAGUCHI Naohito, NAKAZATO Yoichi , SATO Keiki, UEMAE Youji, OHNO Tadao, OKADA Yoshikazu, HORI Tomokatsu |
| Publication date | 2011/08 |
| Summary | The objective of the present study was analysis of results of the prospective clinical trial directed toward the evaluation of therapeutic efficacy of the administration of autologous formalin-fixed tumor vaccine (AFTV) concomitant with fractionated radiotherapy in cases of newly diagnosed glioblastoma multiforme.|Twenty-four patients were enrolled into the clinical trial, while 2 cases were excluded from the final analysis of results. The treatment protocol included aggressive tumor resection, fractionated radiotherapy up to a total dose of 60 Gy, and 3 concomitant courses of AFTV administered with an interval of one week at the late stage of irradiation. |
| DOI | 10.3171/2011.4.jns10377 |
| Document No. | 21568657 |