KONDO Tsunenori
   Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine
   Position   Professor
論文種別 総説
言語種別 日本語
査読の有無 査読あり
招待の有無 招待あり
表題 Pathological Classification of Renal Cell Carcinoma, based on WHO2016 Classification
掲載区分国内
巻・号・頁 pp.1427-1438
著者・共著者 Yoji Nagashima, Aya Yamamoto, Reiko Nakajima, Satoru Morita, Hironori Fukuda, Toshio Takagi, Tsunenori Kondo
担当区分 最終著者
発行年月 2017/12
概要 Pathological classification of renal cell carcinomas (RCCs) has been altered with the impact of novel facts in molecular biology. The WHO2016 classification of RCCs includes the revisions as follows; 1) multilocular cystic RCC has been changed to multilocular cystic neoplasm with low malignant potential, 2)MiT translocation RCC has been introduced encompassing Xp11.2 and 6p21 translocation cases, 3) acquired cystic disease-associated RCC has been introduced as a hemodialysis-related type, 4) several other novel types have been introduced, i.e. clear cell papillary, tubulocystic, succinate dehydrogenase-deficient, hereditary leiomyomatosis RCC-associated, 5) renal medullary carcinoma and post-neuroblastoma RCC were deleted, and 6) novel nuclear grading system based on nucleolar size is recommended to apply to clear cell and papillary RCCs. In this review, we have presented general features of pathological diagnosis of RCCs and novel histological types.