ヤマキ　タカシ   八巻　隆    所属   医学部 医学科（附属足立医療センター）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Prospective direct comparison study of fractional resurfacing using different fluences and densities for skin rejuvenation in Asians.
掲載誌名	正式名：Lasers in surgery and medicine 略　 称：Lasers Surg Med ISSNコード：0196-8092(Print)0196-8092(Linking)
巻・号・頁	39(4),pp.311-4
著者・共著者	Kono Taro, Chan Henry H, Groff William Frederick, Manstein Dieter, Sakurai Hiroyuki, Takeuchi Masaki, Yamaki Takashi, Soejima Kazutaka, Nozaki Motohiro
担当区分	責任著者
発行年月	2007/04
概要	BACKGROUND AND OBJECTIVE:Fractional resurfacing is a new concept of cutaneous remodeling whereby laser-induced zones of microthermal injuryBACKGROUND AND OBJECTIVE:are surrounded by normal untreated tissue. The aim of this study is to compare the efficacy and complications of Fraxel laser treatment when using different fluences and density settings.STUDY DESIGN/MATERIALS AND METHODS:Thirty female Asian patients were enrolled in the study. Group 1 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Group 2 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 8 mJ. The other half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. Group 3 (n = 10); half of the face was treated with eight passes at 125 MTZ/cm2 at an energy setting of 16 mJ. The other half of the face was treated with eight passes at 250 MTZ/cm2 at an energy setting of 8 mJ. Ice pack cooling was used during and after laser treatment. The patients were evaluated for clinical efficacy and treatment-related side effects.RESULTS:Pain, erythema, and swelling were observed to be significantly more evident or persisted longer in patients treated with higher densities and fluences (PRESULTS:<RESULTS:0.01). Patient satisfaction is significantly greater in patients treated with higher fluences (PRESULTS:<RESULTS:0.05), but not in patients treated with higher densities. Hyperpigmentation was observed in two patients.CONCLUSION:Increased density was more likely to produce swelling, redness, and hyperpigmentation when compared to increased energy. Patient satisfaction is significantly higher when their skin is treated with high fluences, but not when patients' skin is treated with high densities.
DOI	10.1002/lsm.20484
文献番号	17457835