TANIAI Makiko
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Associate Professor |
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Article types | Case report |
Language | English |
Peer review | Peer reviewed |
Title | An intensive medical care network led to successful living-donor liver transplantation in late-onset hepatic failure with disseminated Staphylococcus aureus infection |
Journal | Formal name:Clinical journal of gastroenterology Abbreviation:Clin J Gastroenterol ISSN code:(1865-7265)1865-7265(Linking) |
Domestic / Foregin | Foregin |
Volume, Issue, Page | 12(2),pp.112-119 |
Author and coauthor | KURE Rie†, UEHARA Natsumi, INOUE Kazuyuki, KOGISO Tomomi, KODAMA Kazuhisa, TANIAI Makiko, TOKUSHIGE Katsutoshi, NAKAO Masayuki, EGAWA Hiroto, YAMAMOTO Masakazu |
Publication date | 2019/04 |
Summary | Here, we describe a 42-year-old male patient with late-onset hepatic failure (LOHF) due to acute-onset autoimmune hepatitis. At first, his response to steroid therapy was good, but hepatitis relapsed during steroid pulse therapy. Deterioration of liver function caused LOHF, and LOHF has a poor prognosis, particularly when it is complicated by infection. Systemic infection by Staphylococcus aureus resulted in a skin rash and septic pulmonary embolism, and is an absolute contraindication for liver transplantation (LT). In this treatment network, hepatologists and a transplant surgeon cooperated to overcome severe infection and their efforts led to successful transplantation. On-line hemodiafiltration is an indispensable treatment option for acute liver failure. Infection control is crucial for LT and an intensive medical care network led to successful living-donor LT. |
DOI | 10.1007/s12328-018-0904-y |
PMID | 30218430 |