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オオモリ テツペイ
OMORI Teppei
大森 鉄平 所属 医学部 医学科（東京女子医科大学病院） 職種 非常勤講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Efficacy of Calcineurin Inhibitors for Induction of Remission in Intestinal Behçet's Disease. |
| 掲載誌名 | 正式名：Crohn's & colitis 360 略 称：Crohns Colitis 360 ISSNコード：2631827X/2631827X |
| 掲載区分 | 国外 |
| 巻・号・頁 | 4(3),pp.otac017 |
| 著者・共著者 | KAWAGUCHI Takaaki, FUKATA Masayuki, OMORI Teppei, KIYOHARA Hiroki, SUGIMOTO Shinya, NANKI Kosaku, SUJINO Tomohisa, MIKAMI Yohei, KANAI Takanori |
| 発行年月 | 2022/07 |
| 概要 | BACKGROUND:The efficacy of calcineurin inhibitors (CNIs) for induction of remission in intestinal Behçet's disease (intestinal BD) has not been explored.METHODS:A multicenter retrospective case series study of patients with active intestinal BD treated with CNIs (cyclosporin and tacrolimus) was conducted.RESULTS:Of 16 patients, 12 (75%) showed a clinical response and 5 (31.3%) achieved clinical remission after 2 weeks of CNI treatment. Similar efficacy of CNIs was observed even in 7 patients refractory to antitumor necrosis factor-alpha therapies. Endoscopic improvement was observed in 11 of 12 patients.CONCLUSIONS:CNIs may be promising treatment options for refractory intestinal BD. |
| DOI | 10.1093/crocol/otac017 |
| PMID | 36777415 |