水主川 純
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Case report
Language English
Peer review Peer reviewed
Title Successful Pregnancy After Sacrectomy Combined With Chemotherapy and Radiation for Ewing Sarcoma: Case Report and Literature Review.
Journal Formal name:Journal of pediatric and adolescent gynecology
Abbreviation:J Pediatr Adolesc Gynecol
ISSN code:18734332/10833188
Domestic / ForeginForegin
Volume, Issue, Page 28(3),pp.e79-81
Author and coauthor Kakogawa Jun, Nako Takafumi, Kawamura Kazuhiro, Nakamura Shin, Mochiduki Ayako, Kanayama Naohiro, Tanaka Mamoru
Authorship Lead author,Corresponding author
Publication date 2015/06
Summary BACKGROUND:Ewing sarcoma is considered to have a poor prognosis. Recent advances in multidisciplinary management have resulted in a marked improvement in long-term survival.CASE:We describe a case of successful pregnancy in a patient who underwent sacrectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma. The patient was diagnosed with Ewing sarcoma of the sacrum at the age of 16. The ovaries were transposed, the uterus was shielded, and a gonadotropin-releasing hormone agonist was used during treatment to protect ovarian function. The patient spontaneously conceived at the age of 27. After an uneventful pregnancy, the patient delivered a healthy neonate at term by cesarean section.SUMMARY AND CONCLUSIONS:Successful pregnancy and delivery can be achieved after multi-modality treatment with pretreatment intervention for fertility preservation.
DOI 10.1016/j.jpag.2014.06.009
PMID 25823720