水主川　純
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Original article
Language English
Peer review Peer reviewed
Title Noninvasive monitoring of placental oxygenation by near-infrared spectroscopy.
Journal Formal name：American journal of perinatology
Abbreviation：Am J Perinatol
ISSN code：10988785/07351631
Domestic / ForeginForegin
Volume, Issue, Page 27(6),pp.463-8
Author and coauthor Kakogawa Jun, Sumimoto Kazuhiro, Kawamura Takakazu, Minoura Shigeki, Kanayama Naohiro
Authorship Lead author,Corresponding author
Publication date 2010/06
Summary We evaluated the clinical usefulness of near-infrared spectroscopic quantitative measurement of placental oxygenation for the noninvasive estimation of uteroplacental function in pregnant women. We performed a prospective, observational clinical study. Women without complications (N = 15), women with threatened preterm delivery (TPD; N = 6), and women with intrauterine fetal growth restriction (IUGR; N = 6) were enrolled. Measurements of placental tissue oxygenation index (TOI) using the NIRO-300 (Hamamatsu Photonics, Hamamatsu City, Japan) were recorded. Mean TOI was 72.3 +/- 5.3% in women without complications, 72.9 +/- 5.6% in pregnant women with TPD, and 78.7 +/- 3.0% in pregnant women with IUGR. Mean TOI in pregnant women with IUGR was significantly higher than that of the other two groups (P < 0.05). In the IUGR group, although gestational age at measurement on admission was less than that made during hospitalization (P < 0.05), there were no differences in the TOI in relation to gestational age at measurement. Higher TOIs in pregnant women suggest decreased placental function. Monitoring the TOI by near-infrared spectroscopic quantitative measurement may have a high potential for clinical application, particularly in prenatal management.
DOI 10.1055/s-0030-1247600
PMID 20119892