キタハラ　シユウジ   KITAHARA Shuji   北原　秀治    所属   研究施設 研究施設    職種   特任准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	[Cancer stromal cells influence on the tumor angiogenic pattern].
掲載誌名	正式名：Gan to kagaku ryoho. Cancer & chemotherapy 略　 称：Gan To Kagaku Ryoho ISSNコード：03850684/03850684
掲載区分	国内
巻・号・頁	35(12),pp.2250-2
著者・共著者	Kitahara Shuji, Itagaki Hiroko, Ezaki Taichi
発行年月	2008/11
概要	Since the progression and metastasis of solid tumors depend on their local microcirculation, we sought to characterize the tumor angiogenesis three-dimensionally in a highly metastatic mouse melanoma model, B16BL6 melanoma injected with Matrigel into syngeneic C57BL/6 mice by using confocal laser scanning microscopy and transmission electron microscopy. We found that B16 melanoma within Matrigel grew significantly quicker than B16 melanoma alone and was accompanied by altered tumor angiogenesis and avascular area. We characterized the unique patterns of avascular area by using confocal laser-scanning microscopy and transmission electron microscopy.
PMID	19106586