オオメ　ユウスケ   大目　祐介    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	Short- and long-term outcomes of laparoscopic radical gallbladder resection for gallbladder carcinoma: A multi-institutional retrospective study in Japan
掲載誌名	正式名：Journal of hepato-biliary-pancreatic sciences 略　 称：J Hepatobiliary Pancreat Sci ISSNコード：18686982/18686974
掲載区分	国内
巻・号・頁	30(8),pp.1046-1054
著者・共著者	MINAGAWA Takuya,ITANO Osamu,HASEGAWA Shinichiro,WADA Hiroshi,ABE Yuta,KITAGO Minoru,KATSURA Yoshiteru,TAKEDA Yutaka,ADACHI Tomohiko,EGUCHI Susumu,OSHIMA Go,AIKO Satoshi,OME Yusuke,KOBAYASHI Toshiki,HASHIDA Kazuki,NARA Satoshi,ESAKI Minoru,WATANABE Jota,OHTANI Hiromi,ENDO Yutaka,SHIROBE Takashi,TOKUMITSU Yukio,NAGANO Hiroaki
発行年月	2023/08
概要	BACKGROUND/PURPOSE:Laparoscopic resection of gallbladder carcinomas remains controversial. This study aimed to evaluate the surgical and oncological outcomes of laparoscopic procedures for suspected gallbladder carcinoma (GBC).METHODS:In this retrospective study, data regarding suspected GBC treated with laparoscopic radical cholecystectomy before 2020 in Japan, was included. Patient characteristics, surgical procedure details, surgical outcomes, and long-term outcomes were analyzed.RESULTS:Data of 129 patients with suspected GBC who underwent laparoscopic radical cholecystectomy were retrospectively collected from 11 institutions in Japan. Among them, 82 patients with pathological GBC were included in the study. Laparoscopic gallbladder bed resection was performed in 114 patients and laparoscopic resection of segments IVb and V was performed in 15 patients. The median operation time was 269 min (range: 83-725 min), and the median intraoperative blood loss was 30 mL (range: 0-950 mL). The conversion and postoperative complication rates were 8% and 2%, respectively. During the follow-up period, the 5-year overall survival rate was 79% and the 5-year disease-free survival rate was 87%. Recurrence was detected in the liver, lymph nodes, and other local tissues.CONCLUSION:Laparoscopic radical cholecystectomy is a treatment option with potential favorable outcomes in selected patients with suspected GBC.
DOI	10.1002/jhbp.1342
PMID	37306108