マツイ　ケンタロウ   MATSUI Kentaro   松井　健太郎    所属   医学部 医学科（東京女子医科大学病院）    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読なし
招待の有無	招待あり
表題	Nightmares in People with COVID-19: Did Coronavirus Infect Our Dreams?
掲載誌名	正式名：Nature and science of sleep 略　 称：Nat Sci Sleep ISSNコード：11791608/11791608
掲載区分	国外
巻・号・頁	14,pp.93-108
著者・共著者	Scarpelli Serena, Nadorff Michael R, Bjorvatn Bjørn, Chung Frances, Dauvilliers Yves, Espie Colin A, Inoue Yuichi, Matsui Kentaro, Merikanto Ilona, Morin Charles M, Penzel Thomas, Sieminski Mariusz, Fang Han, Macêdo Tainá, Mota-Rolim Sérgio A, Leger Damien, Plazzi Giuseppe, Chan Ngan Yin, Partinen Markku, Bolstad Courtney J, Holzinger Brigitte, De Gennaro Luigi
発行年月	2022/01/24
概要	Introduction:A growing number of studies have demonstrated that the coronavirus disease-19 (COVID-19) pandemic has severely affected sleep and dream activity in healthy people. To date, no investigation has examined dream activity specifically in COVID-19 patients.Methods:As part of the International COVID-19 Sleep Study (ICOSS), we compared 544 COVID-19 participants with 544 matched-controls. A within-subjects comparison between pre-pandemic and pandemic periods computed separately for controls and COVID-19 participants were performed on dream recall and nightmare frequency (DRF; NF). Also, non-parametric comparisons between controls and COVID-19 participants were carried out. Further, we compared psychological measures between the groups collected during pandemic. Ordinal logistic regression to detect the best predictors of NF was performed.Results:We found that people reported greater dream activity during the pandemic. Comparisons between controls and COVID-19 participants revealed a) no difference between groups concerning DRF in the pre-pandemic period and during the pandemic; b) no difference between groups concerning nightmare frequency in the pre-pandemic period; and c) COVID-19 participants reported significantly higher NF than controls during pandemic (p = 0.003). Additionally, we showed that a) anxiety, depression, post-traumatic stress-disorder (PTSD) symptom scores were higher in COVID-19 participants than controls; and b) quality of life and health as well as wellbeing (WHO-5) scores were significantly higher in controls than COVID-19 participants. Finally, ordinal logistic regression indicates that DRF (p < 0.001), PTSD (p < 0.001), anxiety (p = 0.018), insomnia (p = 0.039), COVID-19 severity (p = 0.014), sleep duration (p = 0.003) and age (p = 0.001) predicted NF.Discussion:Our work shows strong associations between increased nightmares in those reporting having had COVID-19. This suggests that the more that people were affected by COVID-19, the gre
DOI	10.2147/NSS.S344299
PMID	35115852