Kooriyama Shiyun'ichi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Language English
Title Tert promoter mutation, not H3K27M mutation is a prognostic factor for adult thalamic gliomas
Conference The 2021 Society for Neuro-Oncology the 26th Annual Scientific Meeting and Education Day
Conference Type International society and overseas society
Presentation Type Speech
Lecture Type General
Publisher and common publisher◎NITTA Masayuki, MURAGAKI Yoshihiro, KOMORI Takashi, MASUI Kenta, SAITO Taiichi, TSUZUKI SHUNSUKE, FUKUI Atsushi, KORIYAMA Shunichi, ONIDUKA Hiromi, IKUTA Soko, KUWANO Jun, KAWAMATA Takakazu, KUWANO Atsushi
Date 2021/11/18
Venue
(city and name of the country)
Boston,USA(web)
Holding period 2021/11/18~2021/11/21
Society abstract Neuro-Oncology 23(Supplement6),vi118–vi119 2021
Summary Purpose
Thalamic diffuse glioma is classified as WHO grade 4 as Diffuse midline glioma, H3K27M mutation if H3K27M mutation was found regardless of its histological findings, but the significance of H3K27M mutation is not clear compared with pediatric cases. We aimed to find genetic prognostic factors in adult thalamic diffuse gliomas.

METHODS
Pathological diagnosis, genetic abnormalities, and clinical course of adult newly diagnosed thalamic gliomas diagnosed and treated at our institution from July 2007 to March 2020 were retrospectively analyzed.