Hoshino Takao
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
|
Article types | Case report |
Language | English |
Peer review | Peer reviewed |
Title | Simultaneous development of acute disseminated encephalomyelitis and Guillain-Barre syndrome associated with H1N1 09 influenza vaccination |
Journal | Formal name:Internal Medicine Abbreviation:Intern Med ISSN code:13497235 |
Volume, Issue, Page | 51(12),pp.1595-1598 |
Author and coauthor | Hoshino Takaho†*, Uchiyama Yumiko, Ito Eiichi, Osawa Shunsuke, Ohashi Takashi |
Authorship | Lead author,Corresponding author |
Publication date | 2012/06 |
Summary | A 36-year-old man was admitted to our hospital because of urinary retention and muscle weakness affecting all 4 limbs after receiving a H1N1 09 influenza vaccination. Magnetic resonance imaging demonstrated multiple lesions in his brain and spinal cord. Furthermore, nerve conduction study showed acute sensorimotor neuropathy, and anti-GM2 antibodies were detected in his serum. Based on the temporal association and exclusion of alternative etiologies, we made a diagnosis of acute disseminated encephalomyelitis (ADEM) and Guillain-Barré syndrome (GBS). To our knowledge, this is the first case of co-morbid ADEM and GBS after influenza vaccination with positive anti-ganglioside antibodies. |
DOI | 10.2169/internalmedicine.51.7132 |